Want to save your brain? Open a cognitive ‘savings account’ – GoCogno.com

Compound interest is the greatest invention ever. Albert Einstein

Theres some dispute whether Einstein actually said that, but there is no question that compounding is a powerful, powerful force.

You know what compounding interest can do for your money, right? Well, wait until you hear what it can do for your cognition. Which is what I want to talk about today.

You need to make some changes in your life, and you need to make them stick.

Hi, Im Tony Dearing of GoCogno.com, the website for people with mild cognitive impairment.

To Go Cogno is to defend your cognition in a way that that gives you the best possible chance of slowing, halting or reversing whatever cognitive loss youre experiencing.

Its the basis of my book, I Want My Mind Back, and toward the end of the book, I break it down into the seven basic concepts that I call the Go Cogno Credo. Right now, Im doing a series of videos where I talk a little more about each of those concepts.

This is part three, where I talk about the C in Go Cogno. It stands for: Compound your way to a better outcome.

Heres what I mean by that. If you hope to change the course of your cognition for the better, you need to make some changes in your life, and you need to make them stick.

You need to embrace healthy lifestyle choices like these, and turn them into habits.

The way to get results is by making small, specific changes one week at a time.

But with health behavior change, success depends on the way you approach it.

The wrong way is the New Years resolution method, where you set out with the best of intentions, but you fail because your goal was too vague or too ambitious. So dont do that. Do what works instead.

The right way to get results is by making small, behavior-specific changes one week at a time.

Dont say, Im going to get more exercise. Instead, say, Tomorrow, Im going to walk around the block once. And then gradually increase from there.

Dont say, Im going to give up soda. Instead, say, Im going to drink one less soda every day and replace it with a bottle of kombucha. Then you lock in that habit and continue to cut back a little more each week.

These changes may seem small, but they add up. They compound, the same way interest compounds on money you put in the bank.

In fact, thats a perfect way to think about it.

Youre determined to save your brain, right? So heres what you do. You open a cognitive savings account, and you start making regular deposits into it.

These changes may seem small, but they add up. They compound.

Those deposits are in the form of small changes in health behavior, that you turn into habits. You earn compounding interest on those deposits, and over time the dividend can be a better cognitive outcome.

In the real world, thats how successful health behavior change happens. So put compounding to work for you. Commit to the process and start making those modest weekly deposits.

Of course, I go much deeper into all of this in my book, and if you want to learn more about that, I invite you to read the first chapter for free here.

See you next Sunday. Until then, as always, be kind to your mind.

G Grind it out: What superpower helps people halt memory loss? Sheer relentlessness

O Orient yourself toward action: Why the best medicine for MCI may not be a pill

C Compound your way to a better outcome

O Optimize for maximum benefit

G Go with your gut

N Know your numbers

O Overindulge in self-care

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Want to save your brain? Open a cognitive 'savings account' - GoCogno.com

Most Definitive & Accurate Study on Global Health & Fitness Club (Gym) Market: Insights & Forecast With Potential Impact Of COVID-19…

The global health and fitness club market is estimated to reach US$96.6 billion in 2024, growing at a CAGR of 7.70% for the period spanning from 2020 to 2024. The factors such as increasing per capita disposable income, growing urban population, increasing obesity, rising fitness clubs and gym, inclination towards health clubs for fitness are expected to drive the market. However, growth of the industry will be challenged by increasing physical outdoor activity, increased cost and increasing demand for home equipments. A few notable trends include rise of lifestyle related illness, influence of social media, increasing number of health clubs and memberships, technology advancement, increasing healthcare costs, increasing health conscious audience and growing hybrid studios.

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The global health and fitness club market is expected to grow in future owing to rising awareness among people to avail healthy lifestyle, increasing number of lifestyle-oriented diseases and rising incidences of obesity. In terms of geographical areas, America is the major contributor to the global health and fitness club memberships supported by growing millennial population and rising obesity. Asia is the fastest growing market for health and fitness club with attractive membership fees offered by fitness clubs and increasing spending on marketing and advertisement.

Scope of the report:

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Table of Content

1. Introduction1.1 Fitness Clubs1.2 Different Fitness Centers1.3 Different Facilities and Services

2. Impact of COVID-192.1.1 Fall in Memberships2.1.2 Gyms Bankruptcy2.1.3 Rising Sales of Home Fitness Equipments

3. Global Health and Fitness Club Market Analysis

3.1 Global Health and Fitness Club Market by Value3.2 Global Health and Fitness Club Market Forecast by Value3.3 Global Health and Fitness Penetration Rate by Region3.4 Global Health and Fitness Club Market by Region3.5 Global Health and Fitness Club Membership3.6 Global Health and Fitness Club Membership Forecast3.7 Global Health and Fitness Club Membership by Region3.8 Global Number of Gym by Region

4. Regional Health and Fitness Club Market Analysis4.1 North America4.1.1 North America Health and Fitness Club Market by Value4.1.2 North America Health and Fitness Club Market Forecast by Value4.1.3 North America Health and Fitness Club Membership4.1.4 North America Health and Fitness Club Membership Forecast4.1.5 Number of Gyms in North America4.1.6 Number of Gyms in North America Forecast4.1.7 U.S. Gym Market by Value4.1.8 U.S. Gym Market Forecast by Value4.1.9 U.S. Gym Membership4.1.10 U.S. Gym Membership Forecast4.1.11 Number of Gyms in the U.S.4.1.12 Number of Gyms in the U.S. Forecast4.2 Europe4.2.1 Europe Health and Fitness Club Market by Value4.2.2 Europe Health and Fitness Club Market Forecast by Value4.2.3 Europe Health and Fitness Club Membership4.2.4 Europe Health and Fitness Club Membership Forecast4.2.5 Number of Gyms in Europe4.2.6 Number of Gyms in Europe Forecast4.3 Asia-Pacific4.3.1 Asia-Pacific Health and Fitness Club Market by Value4.3.2 Asia-Pacific Health and Fitness Club Market Forecast by Value4.3.3 Asia-Pacific Health and Fitness Club Membership4.3.4 Asia-Pacific Health and Fitness Club Membership Forecast4.3.5 Number of Gyms in Asia Pacific4.3.6 Number of Gyms in Asia Pacific Forecast

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5. Market Dynamics5.1 Growth Drivers5.1.1 Increasing Per Capita Disposable Income5.1.2 Growing Urban Population5.1.3 Increasing Obesity5.1.4 Rising Fitness Clubs and Gym5.1.5 Inclination Towards Health Clubs for Fitness5.2 Key Trends & Developments5.2.1 Rise of Lifestyle Related Illness5.2.2 Influence of Social Media5.2.3 Increasing Number of Health Clubs and Memberships5.2.4 Technology Advancements5.2.5 Increasing Healthcare Costs5.2.6 Increasing Health Conscious Audience5.2.7 Growing Hybrid Studios5.3 Challenges5.3.1 Increasing Physical Outdoor Activity5.3.2 Increased Cost5.3.3 Increasing Demand for Home Equipments

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In Defense Of Not Cooking Every Night – HuffPost

Allow us to introduce you to a slightly delayed and unexpected new years resolution: the promise not to cook every night.

Although a lofty goal, planning to concoct a fresh meal every night of the week seems to be a slightly unattainable endeavor. There are too many variables to consider: Do I have all the ingredients I need? Do I have time to cut endless vegetables, cook them, clean the kitchen and do it all over again tomorrow? What should I even make? To put it simply, cooking is exhausting because it isnt just about cooking. It involves preparation and then post-cooking cleanup, not to mention grocery runs and recipe research.

What would happen if we were to, perhaps, opt to cook every other dinner at home? Would our self-worth disintegrate, our body image self-destruct and our dedication to a healthy lifestyle falter if we chose to consume takeout, dine-out or leftovers a few times a week? Turns out, the answer is a resounding no.

Lest you think wed provide you with an idea not backed up by some sort of science, think again! The argument to avoid cooking every night actually has both nutritional and psychological substantiation especially in the midst of a life-changing global pandemic.

KIT8 via Getty Images

Lets start with some data. Subscription service Freshly recently led a survey of 2,000 Americans investigating the ways in ways the pandemic has impacted their 2021 health goals and resolutions. The studys general findings support the idea that realistic goals (cook more, but not every night vs. cook every night) actually resonate with the average citizen more than absolutes.

Specifically, 67% of respondents revealed that theyre opting for smaller, more achievable micro-goals this year. These include eating less takeout (38%), maintaining ones weight over losing some (38%) and eating more nutritious lunches (which dont necessarily need to be homemade) while working from home (35%).

The results of the study likely have much to do with the psychological implications of self-promises to prepare dinner every night. A study of families with kids did confirm that families who have 7+ meals/week at home have higher levels of stress and less prep time, explains nutrition and weight loss expert Dr. Nona Djavid. Eating out might take some stress out of the chaos and work that goes into preparing frequent meals for the family.

While, generally speaking, home-cooked meals tend to be healthier, a dishs nutritional value actually depends on the dish itself. You can eat unhealthy food at home and dine out on a healthy meal at a restaurant, Djavid said. This depends on the ingredients you use to cook and/or the meal you order at the [eatery].

The way the average American approaches cooking also affects the psyche. It is important to acknowledge that cooking can be deemed stressful if it is looked at as a task rather than something enjoyable, said Dr. Markesha Miller, a licensed psychotherapist. Cooking every other day as opposed to every day allows for some element of joy to remain in the activity and prevents it from being a daunting routine.

April Brown, a psychotherapist, proposes even more direct options. If you think you will make five meals at home each week, set your expectation to three, she advises. If you set realistic expectations in the kitchen, itll allow you to feel more in control of your life which is something we need now more than ever.

However convincing scientific-adjacent arguments are, you may be more convinced by the personal anecdotes of people whove given up cooking every day. An on-the-surface Google search of the terms in defense of not cooking every night yields the sort of evidence that will likely convince most that getting healthy isnt strictly related to our ability and disposition toward cooking (I Stopped Cooking Dinner and it Made Me a Better Mom! and Is Cooking Dinner Every Night a Chore For You? are some of the top results).

Of course, the alternate reality weve been existing in for close to a year has had a major influence on the topic at hand. In the pre-COVID-19 years, we justified walking away from our new years resolution to cook every night by telling ourselves that heading out for dinner with friends was a well-deserved treat following a hectic day at the office. In 2021, that excuse doesnt hold up anymore: What office? What restaurant? What friends?

As a result, not following through with our beginning-of-the-year promises might actually result in greater self-disappointment in 2021. Given the heartbreak and hardships weve collectively been experiencing since March, slaloming around avoidable regrets should really be our modus operandi.

And so, here we are, encouraging you to order Indian on a Monday, eat the leftovers on a Tuesday and perhaps even order a takeout salad on a Thursday. You might end up actually enjoying cooking throughout the other weekdays. After all, its OK not to cook a few times a week, that is.

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In Defense Of Not Cooking Every Night - HuffPost

Inspiring Communities Partners with Wellocity Health to Deliver National DPP Online – PR Web

I would recommend any DPP organization who is considering online programs to consider Wellocity.

SAN FRANCISCO (PRWEB) January 20, 2021

Inspiring Communities, a nonprofit organization based in Richmond, CA with full CDC recognition for delivering in-person National Diabetes Prevention Program (National DPP), has partnered with Wellocity Health to deliver the National DPP online in English and Spanish. Online delivery provides convenient access to participants from anywhere at any time via their mobile device or computer to fit within a busy lifestyle to prevent type 2 diabetes.

The partnership with Wellocity enables Inspiring Communities to increase access, extend its participant base with employers and health plans, and make the best use of a limited supply of lifestyle coaches. Wellocity provides a turnkey HIPAA compliant telehealth platform designed for CDC recognized NDPP organizations enabling virtual and distance learning delivery.

The Wellocity platform has allowed Inspiring Communities lifestyle coaches to easily adapt to online delivery and enabled them to engage participants outside the class using messaging and a community for support. With a complete solution for National DPP that includes a branded participant journey, lifestyle coach portal, participant apps, customized content, scheduling, and reporting the Inspiring Communities team can now spend more time engaging the participants to improve retention and outcomes.

Being a DPP Coordinator requires me to be in contact with my healthy lifestyle coaches and participants, said Minda Chai, DPP Coordinator for Inspiring Communities. Having Wellocity to support us gives us the boost to encourage our participants to make healthier lifestyle changes. Our participants really enjoy the Wellocity App and how easy it is to use and share ideas and recipes. I would recommend any DPP organization who is considering online programs to consider Wellocity.

It is an honor to partner with a community-based organization with an extremely dedicated staff to adapt the program to its target audience and help it build a brand that is recognized by the public, employers, and health plans for secure and easy to use lifestyle change programs, said Sameer Kanagala, CEO of Wellocity Health.

About Inspiring CommunitiesInspiring Communities, a nonprofit organization based in Richmond, CA was founded in 2009 and has achieved full CDC recognition for delivering in-person National Diabetes Prevention Program (National DPP). Inspiring Communities is a Medicare Diabetes Prevention Program (MDPP) supplier and a Medi-Cal Diabetes Prevention Program (DPP) provider.

To learn more about Inspiring Communities, please visit: https://www.inspiringcommunities.org/

About Wellocity HealthWellocity Health is a digital therapeutics company that offers a telehealth platform for delivering evidence-based personalized lifestyle change programs focused on preventing diabetes and heart disease. The Wellocity platform enables CDCs National Diabetes Prevention Program (DPP) and other lifestyle change and self-management programs to be delivered in virtual and telehealth mode to increase access, improve outcomes and make the best use of a limited supply of lifestyle coaches and certified diabetes educators. Wellocity powers branded diabetes prevention programs for health systems, health plans, community-based organizations, and pharmacies.

Twitter: https://twitter.com/WellocityHealth

Facebook: https://www.facebook.com/WellocityHealth

LinkedIn: https://www.linkedin.com/company/wellocity-health

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Dont let scammers tip the scales of slaying your New Year’s Resolution – Beauregard Daily News

Attorney General| Jeff Landry

In a perfect world, someone hoping to have a more healthy 2021 by losing weight could do so by simply taking a pill, wearing a patch, or drinking a detox tea. Unfortunately, medical data points otherwise; but that is not stopping scammers trying to take advantage of new year wellness resolutions, warns Louisiana Attorney General Jeff Landry.

Attorney General Landry today issued a consumer alert cautioning Louisiana residents of phony weight loss products.

Pursuing a healthy lifestyle is a great idea, said Attorney General Landry. But I strongly encourage consumers to be cautious when purchasing anything that promises weight loss.

According to the Federal Trade Commission (FTC): bogus diet products, centers, and programs are the top reported complaint amongst health-care related scams.

Scammers tend to promise weight loss products that melt, burn, or dissolve unwanted fat. They use these tricks to promote unproven materials with little to no medical testing.

How to recognize if a weight loss product isFAKE:

The product claims weight loss without diet or exercising.

The product promises instant and permanent weight loss.

Claims stating that in order to lose weight, all you have to do is take this pill, wear this patch, or apply this cream.

The product lacks an ingredient list or is on theFDAs list of potentially harmful weight loss products.

The product cites a long list of clinical studies that are unrelated to the product, outdated, or performed on animals not humans.

Attorney General Landry encourages consumers to report deceptive ads and products to the FTC by calling 877-FTC-Help. He also recommends checking out theNational Institute of Healths Dietary Supplement Fact SheetsandNutrition.gov, a USDA-sponsored website that offers credible information to help you make healthful eating choices.

To learn more about scams and fraud, visitwww.AGJeffLandry.comor call Attorney General Jeff Landrys Consumer Protection Hotline at 800-351-4889.

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Dont let scammers tip the scales of slaying your New Year's Resolution - Beauregard Daily News

Key trends that will shape the future of Nanomedicine Market to 2027 | GE Healthcare, Johnson & Johnson, Mallinckrodt plc The Courier – The…

A Basic Introduction to Nanomedicine Market.

The Nanomedicine market report emphasizes on latest data such as driver, emerging trends, and opportunities. This document also covers other important information such as size, restraints, share, challenges, and major players for the forecast period of 2021-2028. The report includes the SWOT analysis of leader companies from the global Nanomedicine market. It also enlists and analyzes the most recent market developments shaping the future of the foremost players and industry.

The report puts a special emphasis on key driving and restraining factors for the market, along with a comprehensive study of the emerging trends and future developments of the market. The report further provides an elaborate study of micro-and macro-economic aspects that are anticipated to influence the demand for the market.

Inquire for a sample copy of the report @ https://www.stratagemmarketinsights.com/sample/9943

Major players covered in this report: GE Healthcare, Johnson & Johnson, Mallinckrodt plc, Merck & Co. Inc., Nanosphere Inc., Pfizer Inc., Sigma-Tau Pharmaceuticals Inc., Smith & Nephew PLC, Stryker Corp, Teva Pharmaceutical Industries Ltd., UCB (Union chimique belge) S.A

Following the fundaments, the market is segmented on the basis of geography:

This report studies the top players, focuses on product capacity, production, value, consumption, market share and growth opportunity from this geographies, covering basis of geography: North America (U.S., Canada, Mexico), Europe (U.K., France, Germany, Spain, Italy and Rest of Europe), Asia Pacific (China, Japan, South Korea, ASEAN, India, Rest of Asia Pacific),Latin America (Brazil, Argentina, Colombia, and Rest of L.A.), Middle East and Africa (Turkey, GCC, UAE and South Africa Rest of Middle East).

Results of the recent scientific undertakings towards the development have been studied. Nevertheless, the factors affecting the leading industry players to adopt synthetic sourcing of the market products have also been studied in this statistical surveying report. As per the report, Nanomedicine market revenue in the year 2020 was USD XX million and is expected to reach USD XX million in the year 2028 at XX% CAGR. It describes current changing market trends to help our clients make astute decisions accordingly. We are also ready to serve with a customized report. According to the need of the clients, this report can be customized and available in a separate report for the specific region.

**NOTE:Our analysts monitoring the situation across the globe explains that the market will generate remunerative prospects for producers to post the COVID-19 crisis.

Report Focus:

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Secondary Data Sources That We Refer To:

Annual reports, investor presentations, SEC filings, and press releases of companies operating in the market.Website, reports, and press releases of end-user facilities.

Secondary Research Is Conducted To Derive The Following Information:

Details such as revenues, market share, strategies, growth rate, product & their pricing by region/country for all major companiesNumber of procedures and an average price of proceduresReplacement rate and pricing of capital equipmentMarket dynamics in relation to the market under focus Drivers, restraints, trends, and opportunitiesMarket & technological trends, new product developments, product pipeline

COVID-19 Impact on Global Nanomedicine Market

The market report analyses the impact of Coronavirus (COVID-19) on the industry. Since the COVID-19 virus outbreak in December 2020, the disease has spread to almost 180+ countries around the globe with the World Health Organization declaring it a public health emergency.

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Key trends that will shape the future of Nanomedicine Market to 2027 | GE Healthcare, Johnson & Johnson, Mallinckrodt plc The Courier - The...

2021 healthy living tips with DJ Blatner and ALDI – Yahoo News

National Review

Tulsi Gabbard, the former Democratic representative from Hawaii, on Friday expressed concern that a proposed measure to combat domestic terrorism could be used to undermine civil liberties. Gabbards comments came during an appearance on Fox News Primetime when host Brian Kilmeade asked her if she was surprised theyre pushing forward with this extra surveillance on would-be domestic terror. Its so dangerous as you guys have been talking about, this is an issue that all Democrats, Republicans, independents, Libertarians should be extremely concerned about, especially because we dont have to guess about where this goes or how this ends, Gabbard said. She continued: When you have people like former CIA Director John Brennan openly talking about how hes spoken with or heard from appointees and nominees in the Biden administration who are already starting to look across our country for these types of movements similar to the insurgencies theyve seen overseas, that in his words, he says make up this unholy alliance of religious extremists, racists, bigots, he lists a few others and at the end, even libertarians. She said her concern lies in how officials will define the characteristics they are searching for in potential threats. What characteristics are we looking for as we are building this profile of a potential extremist, what are we talking about? Religious extremists, are we talking about Christians, evangelical Christians, what is a religious extremist? Is it somebody who is pro-life? Where do you take this? Gabbard said. She said the proposed legislation could create a very dangerous undermining of our civil liberties, our freedoms in our Constitution, and a targeting of almost half of the country. You start looking at obviously, have to be a white person, obviously likely male, libertarians, anyone who loves freedom, liberty, maybe has an American flag outside their house, or people who, you know, attended a Trump rally, Gabbard said. The Domestic Terrorism Prevention Act of 2021 was introduced in the House earlier this week in the aftermath of rioting at the U.S. Capitol earlier this month that left five dead. Unlike after 9/11, the threat that reared its ugly head on January 6th is from domestic terror groups and extremists, often racially-motivated violent individuals, Representative Brad Schneider (D., Ill.) said in a statement announcing the bipartisan legislation. America must be vigilant to combat those radicalized to violence, and the Domestic Terrorism Prevention Act gives our government the tools to identify, monitor and thwart their illegal activities. Combatting the threat of domestic terrorism and white supremacy is not a Democratic or Republican issue, not left versus right or urban versus rural. Domestic Terrorism is an American issue, a serious threat the we can and must address together, he said.

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2021 healthy living tips with DJ Blatner and ALDI - Yahoo News

Dr. Nicole Avena Shares Nutrition Tips for Healthy Living in 2021 – Business Wire

NEW YORK--(BUSINESS WIRE)--The start of a new year is often coupled with self-reflection and the desire to adopt healthy lifestyle choices, but this year prioritizing health takes on greater meaning as people look to boost their immune system and prevent illnesses. Holistic health and immunity against common colds go hand in hand according to U.S. National Institutes of Health's National Library of Medicine, healthy individuals should make sure to maintain their immune system to lower the incidence of infection, lessen severity of symptoms, shorten duration of colds, which suggests that regular supplementation could be encouraged for preventing and treating their colds. Nicole Avena, Ph.D., nutrition expert and author of Why Diets Fail, provides recommendations to boost immunity through nutrition, lifestyle changes, and supplementation which can easily be incorporated into ones daily health and wellness routine.

This year, functional nutrition and holistic health will be big whether it is using food as medicine or making diet and lifestyle changes for preventative wellness and increased immunity, says Avena. Depending on what those goals are, whether its fitness improvement or stress reduction, nutritional solutions are available through various foods, vitamins, and supplements that can specifically assist in attaining both holistic health and immune system support.

Below, Dr. Avena recommends ways to support the immune system and reveals how nutrients play a role in immune system functionality and mood regulation.

It is important to consult with your healthcare provider before taking any dietary supplement or changing your diet in a drastic way. Holistic health is a preventative measure and while specific goals can be important benchmarks to make implementing health and lifestyle routines that are manageable and promote overall wellness can help you achieve your goals while also making lasting changes to your overall wellness, adds Avena.

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Dr. Nicole Avena Shares Nutrition Tips for Healthy Living in 2021 - Business Wire

Healthy Living: Set priorities to cope with uncertain year – Norwich Bulletin

By Mariana Batista, For The Bulletin| The Bulletin

The year 2020 is now gone, but we will experience its effects for months to come. It may seem discouraging to make resolutions for the New Year when uncertainty is still ahead, but the end of a year and the start of a new one gives us the motivation to renew our hope and start over.

It was a year of change, many imposed by the restrictions to contain the virus that caught everyone by surprise and demanded flexibility and aptitude to adapt quickly. But we also had the opportunity to rethink our priorities and how much time we should allocate for each area to improve our quality of life.

Prioritizing self-care and mental health will help you prepare for the challenges of 2021, also improving our resilience and well-being. How to start? Here are a few suggestions:

If things are still difficult to manage and affecting your ability to function, it's OK to look for professional help. And, remind yourself of the ebb and flow of life. Nothing is permanent and this too shall pass.

Mariana Batista is practice manager atUCFS Healthcare's New London office.

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Healthy Living: Set priorities to cope with uncertain year - Norwich Bulletin

Healthy Kingsport and HealthFitness | Family | timesnews.net – Kingsport Times News

Healthy Kingsport began several years ago with a group of committed community members who saw the urgency associated with our communitys adverse health trends. The trends showed our community was moving in the wrong direction regarding obesity, physical activity and tobacco use. So, the group dedicated themselves to changing our communitys direction.

Healthy Kingsport evolved over the next few years into a nonprofit organization dedicated to creating a community that actively embraces healthy living by promoting wellness, enhancing infrastructure and influencing policy.

Our work is accomplished by the Collective Impact Modela best practice for solving complex, pressing social issues. This model is designed around a backbone organization (Healthy Kingsport), which serves as the convener of many organizations working toward a common agenda with shared measurements, mutually reinforcing activities and continuous communication.

HealthFitness employs more than 3,000 health professionals across all 50 states. Each day, they work directly with participants to educate, encourage and engage them in caring for their health, similar to Healthy Kingsports efforts. Today, HealthFitness has the privilege of serving 160 clients many of them are employed at Eastman Chemical Co. in Kingsport.

HealthFitness help clients

and their employees by:

Building comprehensive programs that span wellness, fitness, recreation and injury prevention and treatment.

Managing the program on the employers behalf, integrating all their wellness programs into one seamless experience.

Engaging employees and meeting them where they need us most (onsite and online) helps them navigate their wellness journey.

HealthFitness is proud to serve as a sponsor for Healthy Kingsport, which shares our mission of making people healthier where they work, play and live, said program manager Jessica Shutter.

Today, Sullivan County ranks 32nd out of 95 Tennessee counties in the category of Health Outcomes with 24% of adults using tobacco and 38% of adults physically inactive.

These percentages reflect cultural norms that are higher than the national average and cause great concern for our families, friends and neighbors. While these pressing social problems cannot be solved in the near-term, much work is being done to positively impact these percentages and increase the health and well-being of those living in our community.

Healthy Kingsport expresses great appreciation to HealthFitness for supporting the important efforts around health and wellness taking root in Greater Kingsport. The commitments made by this business are yielding positive results for our family members, friends, and neighbors. The focus on health and wellness is also helping our community prosper as existing companies expand and new businesses locate here.

Again, many thanks for working to create a community that actively embraces healthy living!

Healthy Kingsport is a nonprofit organization dedicated to creating a community that actively embraces healthy living by promoting wellness, enhancing infrastructure and influencing policy.

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Healthy Kingsport and HealthFitness | Family | timesnews.net - Kingsport Times News

‘I’ve never felt this happy with myself’: Akron bariatric teen patient finds new lifestyle – Akron Beacon Journal

Betty Lin-Fisher|Akron Beacon Journal

Riley Ickes didnt used to like going to school, but now the 16-year-old cant wait until her school gets back to in-person sessions amidst the COVID-19 pandemic.

Riley thinks a lot of her Ellet High School classmates may not recognize her.

Shes nearly 100 pounds lighter than last March when classes went online at her heaviest 324 pounds. As of this week, she has lost 94 pounds and is still going, thanks to drastic changes in her lifestyle, including nearly daily exercise, diet and bariatric surgery.

More: Summit County Public Health gives drive-thru COVID-19 vaccinations

In September, Riley was one of the first patients to undergo bariatric surgery in a new program at Akron Childrens Hospital. The surgery is not for everyone, but for some patients who have medical conditions that make it difficult for them to lose weight it can be an option, said Dr. Marnie Wagner Walston, a pediatrician who specializes in pediatric obesity medicine and adolescent bariatric surgery.

Walston oversees the hospitals Healthy Active Living program, which provides evaluation and treatment for children and teens who are overweight. The team includes a physician, psychologist, certified nurse practitioner, dietitian and exercise physiologist.

Theres a common misconception that surgery is a quick fix or an easy way out and a patient doesnt have to work, said Walston, who graduated from Firestone High School in 2004.

Patients who want to undergo bariatric surgery still have an eight-to-nine-month process before starting surgery plans, she said.

We're working on healthy lifestyle changes. That might help a patient lose weight without even needing surgery. Thats the ideal situation, Walston said.

But statistics show that for most teens with severe obesity, theyre not going to be successful with behavioral and lifestyle changes alone, she said.

Riley said shes always struggled with her weight.

I've always been a lot bigger than everybody, she said. My mom would take me to different doctors to try to figure out what was going on.

At around age 14, she was diagnosed with polycystic ovary syndrome, an imbalance of hormones, which can also cause fertility issues and obesity. She also had high cholesterol and was pre-diabetic.

Renee Ickes, Rileys mom, said: Shes always been active and shes a good eater but she doesnt eat any different than anyone else. She struggled her whole life and we just tried everything including gym memberships, dieticians and dance classes.

After the diagnosis, they were referred to the Healthy Active Living program.

Everything changed. They're amazing, said Renee.

Surgery was not initially brought up.

She tried all the options and the struggle was there. She just couldnt do it," said Renee Ickes. "The doctor brought it up to us. It took us a while to research and convince everyone it was the right thing.

Adolescent bariatric surgery came about in the 2000s. As procedures have improved, they have become minimally invasive done laparoscopically with minimal incisions and a one- to two-night hospital stay, said Dr. Mark Wulkan, the new chair of Childrens Department of Surgery.

You dont do the operation to be pretty for the prom;it's really about the health benefits, said Wulkan. People think its a cosmetic operation. This is an operation to help reverse a disease [obesity].

There are the same advantages for the patient of doing bariatric surgery in an adult and a teen, which include reducing health risks such as high blood pressure, diabetes, sleep apnea and liver disease, said Wulkan. But studies have shown that those risks are easier to reverse the younger you do the surgery, he said.

That makes the argument that maybe its not a last resort. Maybe its something we should be looking at and it's just one of the tools in your toolbox to treat being overweight," Wulkan said.

He arrived from Atlanta in August. Childrens had already been working on starting the bariatric surgery program before his arrival, but Wulkan, a general surgeon, has a special interest and expertise in bariatric surgery, which he has been performing since 2004. He and Dr. Scott Boulanger will perform the surgeries.

In order for a patient to qualify for bariatric surgery, several factors are considered, including whether the operation outweighs the medical risks and the patients body mass index (BMI) the relationship between height and weight.In addition, the patient must actively participate in a weight-management program for six months.

Even with that, Walston said, not all candidates ultimately have the surgery. There have been three completed (COVID-19 slowed things down) and about 21 patients are working toward surgery. About a quarter of those patients may not pursue surgery, she said.

The patients have to make lifestyle changes, including diet and exercise, before the surgery to make those changes stick after surgery, Wulkan said.

In most pediatric cases, the surgery is a gastric sleeve, where 80 to 85 percent of the stomach is removed. That decreases the capacity of the stomach, so the patient gets full with less. The stomach also produces a hormone that makes you feel hungry. After the surgery, there is less of that hormone, so it decreases your appetite.

It works mechanically and hormonally, Wulkan said.

But that means the body also doesnt signal that it is hungry, Walston said, so patients have to learn how to eat smaller, healthier meals more often. The patients work with experts to make sure theyre eating appropriately and taking vitamins and mineral supplements to make sure there are no nutritional deficiencies.

Surgery helps you reduce the appetite. It's not the fix, said Walston. The surgery itself doesnt remove any weight from the body, but it gives you tools.

The surgerys benefits can be defeated if the patients dont make the lifestyle changes, including exercise and diet, she said.

Candidates for surgery tend to be in their teens, the doctors said, but the team will discuss with a younger patient and family if there is a reason to have the surgery.

"You want to be really thoughtful about the patients emotional ability, ability to be able to live with the implications and understand, Walston said.

Walston is happy that Akron-area adolescent patients have an option for the surgery. Before the hospitals program started, patients had to go to an adult hospital or another region, she said.

Riley enjoys planning and cooking her own meals. She also goes to work out every morning before coming home for online classes while Akron schools are still remote. Riley also works at Walmart after school.

Renee said she doesnt even worry about Riley and her eating habits now.

This kid carries a cooler around with her with chicken. She has her produce and her proteins and she is like an expert in reading all of the labels," Renee said.

Riley is excited to go back to school in person, but concerned about how to keep up the good exercise schedule she's established before school and work.

Her goal weight is 165. Doctors told her shed lose about 75 pounds right after surgery. Shes already exceeded that, and as of this week has lost 94 pounds at 229 pounds.

Her close friends have seen her, but there are a bunch of friends I havent seen since school had let out last March. I dont know what theyre going to say. I'm kind of excited about that.

Shes also excited to get involved with school activities.

With my size, I wasnt comfortable to do anything. I didnt want to. But now if we were back in school, Id probably get into more activities and do more stuff, she said.This week, she ran into her high school band director, who had to do a double-take before he recognized her.

Overall, I feel great. I've never felt this happy with myself, said Riley. She also no longer has high cholesterol and is no longer considered pre-diabetic.

I dont stress out so much. I used to be so concerned when everyone would look at me when I would do something. Now I dont care, and I'm a lot more comfortable with myself.

Riley is especially excited for the day when she can go to Cedar Point and get on a ride. She had avoided until now because she was afraid she wouldnt fit.

Rileys weight-loss journey has changed her career desires. She had been interested in interior design, but now after I went through the clinic and what they do, it really inspired me to want to do that for the kids. She is interested in maybe being a child life advocate or some type of job to work with kids struggling with weight.

Rileys dad, Ron, said it was hard to watch his daughter struggle with her weight and not want to be involved in activities at school.

"With this surgery and the progress shes made, it just totally changed her mental state of mind. I'm starting to see that go-get attitude, he said. For her now to be able to jump in and commit to... taking a hold of nutrition and the routine of the gym, it blows me away to see that.

It's like I have a new daughter, he said.

Beacon Journal staff reporter Betty Lin-Fisher can be reached at 330-996-3724 or blinfisher@thebeaconjournal.com. Follow her @blinfisherABJ on Twitter or http://www.facebook.com/BettyLinFisherABJ To see her most recent stories and columns, go to http://www.tinyurl.com/bettylinfisher

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'I've never felt this happy with myself': Akron bariatric teen patient finds new lifestyle - Akron Beacon Journal

New Years Resolutions: Easy to make, easier to break – NMLiving

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Have you broken your New Years resolution yet? If you have, you are not alone. Research shows nearly 80% of resolutions will ultimately be broken by the second week of February. No one intends to break their New Years resolutions but most of us will because it is a challenge to maintain new and sometimes unrealistic goals beyond January especially in the midst of a pandemic.

One common resolution that consumers make each and every year is to improve their health.According to research, 84% of all consumers are limiting the amount of sugar in their diet, and more than 70% of adults say sugar is the #1 ingredient they are most trying to cut down or avoid completely.

What can be done to make sure that you stick to your resolutions and dont break them this year? Mia Syn, Masters of Science in Human Nutrition (MS) from Columbia University, Registered Dietitian Nutritionist(RDN), knows the importance of healthy living and has come up with a list of health hacks to help people stick with their New Years resolutions.She offered tips and tricks to enjoy your favorite indulgences while doing so in a healthier manner.

Mia Syn, Masters of Science in Human Nutrition (MS) from Columbia University, Registered Dietitian Nutritionist (RDN), is a national on-air nutrition expert, host of Good Food Friday on ABC News 4 and one of the most recognized and trusted young dietitians in the media.With more TV appearances than any other young nutritionist in the country, she has helped millions of viewers, readers and clients learn healthier, sustainable eating habits.

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New Years Resolutions: Easy to make, easier to break - NMLiving

Though The Pandemic Can Make It More Difficult To Live Healthy Lifestyle, Doctors Say Its More Important Than Ever – CBS Baltimore

BALTIMORE (WJZ) The New Year is traditionally a time when people start to try living a new healthy lifestyle. In the middle of a pandemic, doctors say thats more important than ever.

Molly Bell is taking advantage of the warmer than average January temperatures.

Staying sane, trying to find a little fresh air, a little exercise, Bell said.

Something doctors said we all should be doing as we find ourselves stuck at home.

The quarantine 15 is not a joke. Its very, very real, said Dr. Elizabeth Dovec.

Dr. Dovec is the director of Greater Baltimore Medical Centers comprehensive obesity management program. She said the coronavirus is even more of a reason to get your health and weigh under control.

If you do get the virus youll have a better outcome with the virus, youll have a faster and easier recovery without the necessity of hospitalization for other respiratory support and that sort of thing, Dr. Dovec said.

But living a healthier lifestyle can be easier said than done, and the ever-changing world of fad diets and workouts only adds to the confusion.

There is a lot of misinformation out there online which makes it difficult to know what to follow and some of the things out there are dangerous, she said.

Dr. Dovec said its about starting healthy habits like eating three meals a day that are high in protein.

When you skip breakfast and lunch its going to make you crave things that are higher energy source which are higher in glucose and higher in sugar which is the reason we gain weight, she said.

Exercise is also important, and finding the right activity is key to sticking with it.

Right now with the gyms, I understand that a lot of people are still anxious but as you can hopefully you can just look at things online, do a virtual class. Take a walk with a friend just do something creative that you will actually enjoy and hopefully stick with, Dr. Dovec said.

Experts said the hardest part of starting a healthy lifestyle is getting the ball rolling. So, find an activity you like, do some meal prepping and get going.

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Though The Pandemic Can Make It More Difficult To Live Healthy Lifestyle, Doctors Say Its More Important Than Ever - CBS Baltimore

Love Your Health: Living With Intention In 2021 – Greeneville Sun

Here we are, a week into a new month in, thank goodness, a new year. As the buzz from the holidays, sugar, and time off wans, I have to say it feels good to get back in the swing of things. Im a creature of habit. I love structure, routine and schedules. I know, I know. Maybe youre getting back into the swing of things, or you started 2021 with guns blazing, resolutions in hand, ready to go.

While Ive certainly shared that Im a lover of lists, resolutions Im not so big on. I dont do well with setting goals for myself and not completing them. Because of this I like to set mini goals, intentions if you will. If you made grandiose goals for 2021, by all means go for it. If youre like me or those goals are already starting to lose their luster, I thought Id share a few of the things Im doing in this new month and year to regain focus and reinforce healthy habits.

I went on a good old-fashioned grocery store haul. I had spinach, carrots, avocados, apples, beets, grapefruit, peppers, kraut, bananas, almond milk, brown rice, sprouted grain cinnamon raisin English muffins just to name a few healthy items in my cart Saturday. After one too many holiday treats my body, and I suspect yours, is probably craving produce. Dont adopt that diet mentality of skipping snacks and meals, living off diet soft drinks and air. Stock your fridge and pantry with produce and healthy items. Opening a well-stocked fridge with lovely fruits and veggies within reach is often the push you need, that and getting rid of some of the overly processed junk thats crowding your pantry and fridge.

Speaking of produce, I love salads. I pack a salad most every day for my lunch. During the holidays with time off and an abundance of yummy leftovers I fell out of that habit. My go to and the recipe Im sharing below takes minimal effort. Something you can throw together in five minutes. I love my salads with a serving of yummy whole grain crackers, fruit and a little bubbly courtesy of kombucha.

Packable Crunchy Detox Salad with Sesame Ginger DressingFrom the blog Eating Bird Food

1 1/2 cups kale and cabbage mix (can find a premade option or DIY)

1/3 cup bite-size apple chunks (about 1/2 an apple)

1 1/2 Tablespoons rice vinegar

1 teaspoon grated fresh ginger

Instructions: Whisk together all the dressing ingredients in a small bowl. Package salad ingredients in a portable container until ready for lunch. Toss greens with the toppings. Add sliced avocado and drizzle on the dressing. Add a squirt of sriracha if you like to spice things up a bit and enjoy.

I am hitting restart on my training program. I run almost every morning. Ive explained in this little space before that its not only my daily exercise but often my therapy. With a new job in 2020, which meant an earlier wake up time, COVID-19, canceling not only my precious morning runs with my girlfriends and any races I was training for, I fell into a comfortable pattern of just jogging a few miles a day. I havent been doing long runs, cross training, or challenging myself. Im optimistic the races I was training for and looking forward to last year will happen in 2021.

With optimism by my side its time for me to focus on following a training plan. This is by no means meant to make you feel like you should be training for a race. If you like to walk, jog or run, youve decided 2021 is your year to take up one of these good for you physical activities, or its been a minute, Id encourage you to follow a training plan as well. There are so many wonderful, free resources out there. Couch to 5k and Hal Higdon are two of my favorites, both free and great for all levels, training programs.

I am saying no to post holiday food guilt. In the past, Ive spent many a holiday season stressing and attempting to out-exercise my favorite treats. Skipping meals, saying no to my moms homemade Christmas candy, which I love, really just being miserable. Why? One homemade chocolate covered cherry isnt going to make me gain a pound and I am certain that neither myself or you have ever looked back on a Christmas and thought I wish I wouldnt have had that slice of grandmas pie.

One thing I have learned is to focus on making reasonably healthy choices throughout the day. Eating a filling and produce-heavy breakfast and lunch, running not to burn off my meal from the night before but because I love it and it makes me feel good. That salad or run will always be there. Time spent with loved ones, enjoying a beautiful meal will not.

Jessica Barnett is a Southwest Virginia girl married to a Greeneville native, a mom, personal trainer, certified fitness nutrition specialist, runner, herbivore and ice cream lover. To learn about working with Jessica, prospective clients may email jcbarnett616@gmail.com.

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Love Your Health: Living With Intention In 2021 - Greeneville Sun

Clene Nanomedicine Aims to be the Gold Standard in Neurodegenerative Disease – BioBuzz

Clene Nanomedicine, one of Marylands Future 2020 companies, closed a merger with Tottenham Acquisition I Limited that provided the company with a slot on the Nasdaq Exchange and $31.9 million that will be used to advance the companys gold nanocrystal-based treatment for neurodegenerative diseases.

Clene is developing a new class of drugs called bioenergetic nanotherapeutics that harnesses the properties of gold nanocrystals, which are used to amplify bioenergetic reactions in patients in order to drive intracellular biological reactions. Chief Executive Officer Rob Etherington said bioenergetic nanotherapeutics are a clean break from pharmaceutical drug development that uses classical synthetic chemistry.

Using gold as a therapeutic is not a new concept. Gold-salt injections were historically used to treat rheumatoid arthritis decades ago, but were dropped due to health concerns and toxicity issues.

Funds from the merger with Tottenham, a special purpose acquisition company (SPAC), will be used to advance Clenes lead asset, CNM-Au8, a bioenergetic nanocatalyst under development as an add-on treatment for neurodegenerative diseases like Parkinsons disease, multiple sclerosis and Amyotrophic Lateral Sclerosis (ALS). CNM-Au8 is designed to catalyze biocelluar reactions and so far the company has seen the asset live up to its promise in clinical studies.

Although Clenes corporate offices are in Utah, the bulk of the companys research is conducted in Cecil County, Maryland. Approximately three-fourths of the companys employees are located in Maryland, Etherington said. The company conducts all R&D and manufacturing in Maryland, as well as its commercialization activities.

Maryland has been a perfect anchor for Clene, Etherington said.

While the company raised a significant amount of funds through the merger, Etherington said Maryland was one of the companys earliest financial backers through a loan arrangement. He said predicted his company and the state will continue to have a strong relationship in the years ahead.

The state has been a true supporter. It was also gratifying to be recognized as a Future 2020 company because we have built a home in Maryland, he said.

Etherington predicted the next 18 months will be important for the company due to a planned readout of the companys asset. The funds raised in the merger will be used to carry CNM-Au8 into Phase II and Phase III studies that aim to address neurodegenerative diseases of high unmet medical need, such as multiple sclerosis, Parkinsons disease and amyotrophic lateral sclerosis (ALS). CNM-Au8 is currently being assessed in a Phase II study for the treatment of chronic optic neuropathy in patients with multiple sclerosis and is in Phase II and Phase III studies for disease progression in patients with ALS. Both Phase II studies are expected to read out this year. Its also being studied in a Phase II Parkinsons disease trial. The company reported interim data from the study last year and additional data is expected in the first half of 2021. Clene also plans to launch an additional Phase IIb Parkinsons disease efficacy study with CN<-Au8 by the end of the year.

While CNM-Au8 is showing promise, its not designed to replace any medication currently being used by a patient for one of these diseases. Rather, its designed to work alongside those medications. Clenes compound is designed to enhance the intracellular biological actions necessary to repair and reverse neuronal damage, Etherington said.

Clenes gold nanocrystals are grown in treated water and patients drink the product when it is ready. By combining the nanocrystal therapy with ongoing treatments for these neurodegenerative diseases, Etherington said the goal is to reverse neurodegeneration.

We want to let the cell take care of its own housekeeping and enhance whats naturally occurring in the central nervous system, he said.

In addition to the gold nanocrystal compound, Clene is developing a silver and zinc asset for COVID-19. CNM-AgZn17 is Clenes second key asset intended for broad anti-viral and anti-microbial use. A Phase II study is planned in Brazil to treat acutely symptomatic non-hospitalized patients with COVID-19.

Alex Keown is a freelance journalist who writes about a variety of subjects including the pharma, biotech, and life science industries. Prior to freelancing, Alex has served as a staff writer and editor for several publications.

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Clene Nanomedicine Aims to be the Gold Standard in Neurodegenerative Disease - BioBuzz

Global Cancer Nanomedicine Market Booming Demand Leading To Exponential CAGR Growth By 2027 The Courier – The Courier

The Report Titled onCancer Nanomedicine Market Report- Development Trends, Market Size, Industry Opportunities and Competitive Landscape in 2021firstly introduced the Cancer Nanomedicine Industry basics:The report covers the scope, size, disposition and growth of the industry including the key sensitivities and success factors.The report takes into account theimpact of the COVID-19 pandemic on the Cancer Nanomedicine marketand is perfect for precision and accuracy that will help to meet business requirements at affordable rates. By using Cancer Nanomedicine market report, strengths and weaknesses as well as threats and opportunities for the business can be known. Defining the problem and objectives, collecting and generating market data with the supporting statistics, everything is performed in a streamlined process which makes this report highly accurate.

The information of Cancer Nanomedicine market analysis report covers major technological, scientific and economic developments in industrial, pharmaceutical and high technology organizations. This large scale report helps to achieve unmatchable competitive advantage, build more proficient organizations, and secure lasting results.

Market Analysis and Insights: Global Cancer Nanomedicine Market:

Cancer nanomedicine market is expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge Market Research analyses the market to grow at a CAGR of 12.50% in the above-mentioned forecast period.

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The major players who are leading the Cancer Nanomedicine market throughout the globe are:

Market Segmentation

By Type (Inorganic Nanoparticles, Organic Nanoparticles)

By Agent Type (Diagnostic Agents, Therapeutic Agents, Drug Delivery Agents)

Some Of The Major Highlights Of TOC Covers:-

1 INTRODUCTION

1.1 Objectives Of The Study

1.2 Cancer Nanomedicine Market Definition

2 MARKET SEGMENTATION

2.1 Cancer Nanomedicine Markets Covered

2.2 Europe Weight Management Market: Geographical Scope

3 MARKET OVERVIEW

3.1 Drivers

4 EXECUTIVE SUMMARY

4.1 Europe Weight Management Market: Segmentation

5 PREMIUM INSIGHTS

5.1 Increasing Government Initiatives Towards Management And Growing Consumption Of Healthy Diets Are Expected To Drive The Cancer Nanomedicine Market In The Forecast Period Of 2020 To 2027

Continued.

Browse Global Cancer Nanomedicine Market Research Report with detailed TOC: https://www.databridgemarketresearch.com/toc/?dbmr=global-cancer-nanomedicine-market&AS

Global Cancer Nanomedicine Market Scope and Market Size

Cancer nanomedicine market is segmented on the basis of type, agent type, mechanism, cancer type, imaging technique, and phase. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.

Regional Analysis

This section covers regional segmentation which accentuates on current and future demand for Cancer Nanomedicine market across This section covers regional segmentation which accentuates on current and future demand for COVID-19 Cancer Nanomedicine market across North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. Further, the report focuses on demand for individual application segment across all the prominent regions. Further, the report focuses on demand for individual application segment across all the prominent regions.

Get detailed COVID-19 impact analysis on the Cancer Nanomedicine Market:https://www.databridgemarketresearch.com/inquire-before-buying/?dbmr=global-cancer-nanomedicine-market&AS

Key Pointers Covered In The Cancer Nanomedicine Market Industry Trends And Forecast To 2027

The study provides an in-depth analysis, current trends, and future estimations of theglobal Cancer Nanomedicine marketto elucidate the imminent investment pockets.

Comprehensive analysis of factors that drive and restrict the Cancer Nanomedicine market growth is provided.

The Cancer Nanomedicine Industry report provides a qualitative and quantitative analysis of the current External Storage market trends, forecasts, and market size from 2020 to 2027 to determine new opportunities.

Porters Five Forces analysis highlights the potency of buyers and suppliers to enable stakeholders to make strategic business decisions and determine the level of competition in the industry.

Extensive analyses of key segments of the industry help understand the types of products and technologies used across various geographical regions.

About Data Bridge Market Research Private Ltd:

Data Bridge Market Research PvtLtdis a multinational management consulting firm with offices in India and Canada. As an innovative and neoteric market analysis and advisory company with unmatched durability level and advanced approaches. We are committed to uncover the best consumer prospects and to foster useful knowledge for your company to succeed in the market.

Data Bridge Market Research is a result of sheer wisdom and practice that was conceived and built-in Pune in the year 2015. The company came into existence from the healthcare department with far fewer employees intending to cover the whole market while providing the best class analysis. Later, the company widened its departments, as well as expands their reach by opening a new office in Gurugram location in the year 2018, where a team of highly qualified personnel joins hands for the growth of the company. Even in the tough times of COVID-19 where the Virus slowed down everything around the world, the dedicated Team of Data Bridge Market Research worked round the clock to provide quality and support to our client base, which also tells about the excellence in our sleeve.

Data Bridge Market Research has over 500 analysts working in different industries. We have catered more than 40% of the fortune 500 companies globally and have a network of more than 5000+ clientele around the globe.

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Global Cancer Nanomedicine Market Booming Demand Leading To Exponential CAGR Growth By 2027 The Courier - The Courier

Knee injection shows promise as osteoarthritis treatment in mice – Drug Target Review

Scientists have found that a new knee injection using nanomedicine could prevent the effects of osteoarthritis.

A group of scientists have discovered a potential method to cure osteoarthritis. According to the researchers, a simple knee injection could stop the diseases effects. The study was conducted at the University of Pennsylvania, US.

The researchers showed that they could target a specific protein pathway in mice to halt cartilage degeneration over time. Building on that finding, they were able to show that treating mice with surgery-induced knee cartilage degeneration through the same pathway via nanomedicine could dramatically reduce the cartilage degeneration and knee pain.

Our lab is one of the few in the world studying epidermal growth factor receptor (EGFR) signalling in cartilage and from the beginning, we have found that EGFR deficiency or inactivation accelerates osteoarthritis progression in mice, said one of the researchers Associate Professor Ling Qin. Thus, we proposed that its activation could be used to treat osteoarthritis and in this study, we have proven for the first time that over-activating it inside the knee blocks the progression of osteoarthritis.

The researchers compared typical mice with those that had a ligand that bound to EGFR that was over-overexpressed in chondrocytes, the building blocks of cartilage. This overexpression drives the over-activation of EGFR signalling in knee cartilage. When examining them, the mice with overexpressed HBEGF (the EGFR ligand) were found to consistently have enlarged cartilage, meaning that it was not wearing away like the mice who had normal EGFR activity. Moreover, when these mice aged to adulthood, their cartilage was resistant to degeneration and other hallmarks of osteoarthritis, even if their knees meniscus was damaged.

To further prove that the over-activated EGFR was the reason for the mices resiliency, the researchers found that gefitinib treatments, which are designed to block EFGR function, took away the protection against cartilage degeneration.

In a new series of tests, the researchers created nanotherapeutics by attaching a potent EGFR ligand, transforming growth factor-alpha, onto synthetic nanoparticles, to inject into mice who already had cartilage damage in their knees.

Free EGFR ligands have a short half-life and cannot be retained inside of a joint capsule due to their small size, explained Associate Professor Zhiliang Cheng, the co-corresponding authors on the paper. Nanoparticles help to protect them from degradation, restrict them within the joint, reduce off-target toxicity and carry them deep inside dense cartilage to reach chondrocytes.

When mice were injected with these nanotherapeutics, the researchers saw that they slowed cartilage degeneration and bone hardening, as well as eased knee pain. There also were no major side effects seen in the mice who were treated.

While many of the technical aspects of this application still need to be worked out, the ability to stop or slow the course of osteoarthritis with an injection rather than surgery would dramatically change how we feel and function as we age and after injury, said one of the studys co- authors, Dr Jaimo Ahn.

There is a great unmet medical need for a disease-modifying osteoarthritis drug, Qin said. In the future, we will optimise the drug design and test it in large animals before proceeding to clinical trials. We hope our research could lead to a novel drug that will improve the health and well-being of the more than 27 million osteoarthritis patients in the US.

The findings were published in Science Translational Medicine.

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Knee injection shows promise as osteoarthritis treatment in mice - Drug Target Review

Capricor Therapeutics Announces Publication Demonstrating Methods for Enhanced Potency of Cardiosphere-Derived Exosomes – GlobeNewswire

-Enhanced Signaling Pathways Show Increased Potency Through Expression of MicroRNAs-

-Publication Further Supports Capricors Exosome Platform Advancement-

LOS ANGELES, Jan. 19, 2021 (GLOBE NEWSWIRE) -- Capricor Therapeutics, Inc. (NASDAQ: CAPR), a clinical-stage biotechnology company focused on the discovery, development and commercialization of first-in-class cell- and exosome-based therapeutics for the treatment and prevention of a variety of diseases and disorders, announced today the publication, in collaboration with researchers at Cedars-Sinai Medical Center, which demonstrates the utility of pathway-enhancing culture conditions and small molecule inhibitors to retain markers of cell therapy potency. The publication titled, Small molecule inhibitors and culture conditions enhance therapeutic cell and EV potency via activation of beta-catenin and suppression of THY1 was published in the international peer-reviewed journal, Nanomedicine: Nanotechnology, Biology and Medicine.

This data from this publication is of significant importance to Capricor because it demonstrates our approach to enhance potency of cells by targeting select signaling pathways. The ability to manipulate cells provides read through to our exosome product candidates which are being engineered to treat specific diseases. We have dedicated the last few years at Capricor to understanding the molecular composition of our exosomes products in order to identify microRNAs of interest for therapeutic development, said Dr. Linda Marbn, Ph.D., CEO of Capricor. This data was the foundation of our new platform, which has allowed us to expand our reach to engineering exosomes that contain RNAs for targeted therapeutic delivery. Further, this elucidation of the mechanisms that are driving potential potency of our cell therapy, CAP-1002 and the exosomes they secrete, correlate to some of the promising clinical data we have seen to date in Duchenne muscular dystrophy.

Key findings include:

Dr. Marbn continued, We know that the exosome is natures delivery system and can serve to carry a variety of biologic signals directly to the cell. Now, we have demonstrated that cells can make exosomes loaded with specific and powerful biologic signals. From these early studies, we have launched our platform which will include vaccines, treatment of monogenic diseases, as well as other targets. We plan to announce further pipeline expansion of our exosome-based product candidates by mid-2021.

The work at Cedars-Sinai Medical Center was supported by NIH R01124074; work by Capricor was supported by the Office of the Assistant Secretary of Defense for Health Affairs, through the Peer Reviewed Medical Research Program under Award No. W81XWH-16-1-0712. Opinions, interpretations, conclusions and recommendations are those of the author and are not necessarily endorsed by the Department of Defense.

About Capricor Therapeutics

Capricor Therapeutics, Inc. (NASDAQ: CAPR) is a clinical-stage biotechnology company focused on the discovery, development and commercialization of first-in-class cell and exosome-based therapeutics for the treatment and prevention of diseases. Capricor's lead candidate, CAP-1002, is an allogeneic cell therapy that is currently in clinical development for the treatment of Duchenne muscular dystrophy and the cytokine storm associated with COVID-19. Capricor is also investigating the field of extracellular vesicles and exploring the potential of exosome-based candidates to treat or prevent a variety of disorders. We are now developing two potential vaccines for COVID-19 as part of our exosome platform.For more information, visitwww.capricor.comand follow the Company onFacebook,InstagramandTwitter.

Cautionary Note Regarding Forward-Looking Statements

Statements in this press release regarding the efficacy, safety, and intended utilization of Capricor's product candidates; the initiation, conduct, size, timing and results of discovery efforts and clinical trials; the pace of enrollment of clinical trials; plans regarding regulatory filings, future research and clinical trials; regulatory developments involving products, including the ability to obtain regulatory approvals or otherwise bring products to market; plans regarding current and future collaborative activities and the ownership of commercial rights; scope, duration, validity and enforceability of intellectual property rights; future royalty streams, revenue projections; expectations with respect to the expected use of proceeds from the recently completed offerings and the anticipated effects of the offerings; and any other statements about Capricor's management team's future expectations, beliefs, goals, plans or prospects constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not statements of historical fact (including statements containing the words "believes," "plans," "could," "anticipates," "expects," "estimates," "should," "target," "will," "would" and similar expressions) should also be considered to be forward-looking statements. There are a number of important factors that could cause actual results or events to differ materially from those indicated by such forward-looking statements. More information about these and other risks that may impact Capricor's business is set forth in Capricor's Annual Report on Form 10-K for the year ended December 31, 2019 as filed with the Securities and Exchange Commission on March 27, 2020 and in our Quarterly Report on Form 10-Q for the quarter ended September 30, 2020 as filed with the Securities and Exchange Commission on November 13, 2020. All forward-looking statements in this press release are based on information available to Capricor as of the date hereof, and Capricor assumes no obligation to update these forward-looking statements.

CAP-1002 is an Investigational New Drug and is not approved for any indications. None of Capricors exosome-based candidates have been approved for clinical investigation.

For more information, please contact:

Media Contact:Caitlin Kasunich / Raquel ConaKCSA Strategic Communicationsckasunich@kcsa.com/ rcona@kcsa.com212.896.1241 / 212.896.1204

Investor Contact:Joyce AllaireLifeSci Advisors, LLCjallaire@lifesciadvisors.com617.435.6602

Company Contact:AJ Bergmann, Chief Financial Officerabergmann@capricor.com310.358.3200

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Capricor Therapeutics Announces Publication Demonstrating Methods for Enhanced Potency of Cardiosphere-Derived Exosomes - GlobeNewswire

In a union centered around longevity, Centura Health has joined forces with the Kit Carson County Health Services District (KCCHSD). – Burlington…

The assurance of longevity comes from this. The people who use our facilities will continue to get the best treatment, stated Kindra Mulch, RN, Director of Administrative Services for KCCHSD.

Were ensuring future generations of Kit Carson County residents have access to health care, added Centura Vice President of Integration Josh Neff.

The union became official in mid-January with a two-year contract amid the hopes of continuing the relationship for many years.

Centura Health is the largest health care network in Colorado and Western Kansas. It is a faith-based nonprofit organization formed in 1996 by Adventist Health System and Catholic Health Initiative. Centura Health has 21,000-plus mission-centered professionals sharing the organizations ministry and mission to extend the healing ministry of Christ by caring for those who are ill and by nurturing the health of the people in its communities.

Among the services Centura will provide is helping to vet and employ a permanent CEO for the KCCHSD. Darcy Howard has been CEO in an interim capacity since mid-summer, but has not expressed an interest in the position permanently. Howard has said she will remain onboard as long as the process takes to bring in her replacement.

Centura will also help and advise in a variety of other capacities, including operations, finance, quality, human resources, patient/safety experience, service line development, and additional health care providers including specialists if necessary, while not stepping on the toes of those providers currently working with the district.

Centura has no intent, nor do we have the capability to make sweeping staff changes, Neff stressed. Centura will consult with the board, but make no decision on staff.

These folks have been in the community a while, established patient care. We want to be careful to point out this is not a Centura-or-nothing situation.

There is no ownership change in this agreement. The KCCHSD Board retains all decision-making authority for the district, and Centura does not share in any financial or operational risk.

Also, Centura will have no say in charges administered by the KCCHSD. Howard acknowledged any price decisions are made with the help of a service named Chargemaster and are entirely separate from this union.

In fact, Neff noted that Centura has been working with Governor Jared Polis task force to reduce medical costs in the state.

We understand the cost of health care is expensive too expensive, Neff stated.

In other words, those receiving services from KCCHSD will continue to get the best treatment available, Howard noted.

KCCHSD has always put our patients and our communities first, and the relationship with Centura will not change that. Our patients will continue to maintain the same high-quality interaction with the hospital and our providers, Howard declared. Centura Health has a number of prestigious awards and honors recognizing their outstanding care, quality outcomes and patient satisfaction. We are confident our relationship will serve to help KCCHSD continue to achieve our goals of providing high quality patient care, patient experience and outcomes.

Howard commented that the decision was made to include Centura because, like many rural hospitals, Kit Carson County Memorial Hospital simply needed help to keep its doors open, particularly in the COVID-19 pandemic. While the quality of service has never been affected, maintaining a hospital is anything but cheap.

The rural healthcare landscape is complex and seeing rapid change; moreso now than any time in our history. The industry has seen over 100 independent critical access hospitals in communities just like ours across the country struggle to the point of closing the doors since 2010, with more than 600 rural hospitals vulnerable to closure today, Howard pointed out. The challenges brought on by the COVID-19 pandemic will only increase that for many rural hospitals. Many of the critical access hospitals that are surviving today are partnering with a larger organization or system to give them additional layers of support and help.

Neff added, What we do well is understand the needs of the rural community, Neff stated, adding that Centura is able to translate bigger systems into a local level is key to the success of such a union. He noted that it allows staunchly independent rural hospitals to maintain their independence while maintaining the highest quality of health care.

Stability can be a physical thing and an emotional thing. They are looking for both, Neff continued.

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In a union centered around longevity, Centura Health has joined forces with the Kit Carson County Health Services District (KCCHSD). - Burlington...

Life extension health, rejuvenation and longevity – The Business Times

THE relentless pursuit of the elixir of youth has spurred anti-ageing research in attempts to achieve the triple goals of life extension, namely, the triumvirate of healthy lifespan, rejuvenation and longevity.

Sirtuins are a family of cellular enzymes that are powered by a chemical compound called nicotinamide adenine dinucleotide (NAD). They play an important role in preventing diseases and even reversing some aspects of ageing.

Studies have shown that increased sirtuin activity in mammals has been associated with a delayed onset of age-related diseases and increased longevity.

Increased sirtuin activity appears to inhibit nerve degeneration and reduces the development of cardiovascular and metabolic diseases (such as diabetes mellitus and abnormal lipid levels).

Hence, if sirtuin activity can be increased using compounds that can boost its activity (STACs or Sirtuin Activating Compounds), the use of STACs can potentially help a person stay healthy longer, even if longevity is not affected.

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Resveratrol

Resveratrol is a natural plant phenol STAC found in the skin of red grapes and other fruits such as blueberries and cranberries. Contrary to common belief, red wine contains very little of it. Resveratrol has been shown to have life-extending properties in studies on lower-order species such as yeast and nematodes, but this effect has marginal reliability in higher-order species. Nevertheless, it has been shown to have potentially beneficial effects.

Before you start taking large doses of resveratrol, you may be surprised to know that it is a Janus-faced compound. Low dietary doses may suffice to elicit the biological responses required to optimise the body's defence mechanisms against incipient disease. But at high doses, it behaves in a contrarian manner.

At low doses, resveratrol induces responses that overlap with the female hormone oestradiol. Low-dose effects seen in animal and human studies include beneficial metabolic effects such as more efficient glucose reduction in diabetics, reducing the development of obesity and non-alcoholic fatty liver disease, protecting against arterial degeneration, delaying development of neurodegeneration, and improving motor and cognitive functions.

At high doses, resveratrol has an anti-oestrogen effect which suggests that it may reduce the risk of oestrogen-dependent cancers. This Janus-faced hormetic effects of resveratrol may partly explain the French paradox, where there is a reduced incidence of cardiovascular diseases and certain types of cancer in some populations despite their consumption of high-fat diets.

NAD

NAD is an important molecule that is essential for over 500 enzyme reactions in the body which impact metabolism, ageing, cell death, DNA repair, and gene expression. Hence, NAD plays a pivotal role in human health span and longevity and is a necessary substrate for sirtuin enzymatic activity.

In mammalian cells, NAD is mainly generated by the conversion of nicotinamide (a soluble form of Vitamin B3) into nicotinamide mononucleotide (NMN) followed by its combination with another molecule to form NAD. There is also another precursor, nicotinamide riboside (NR), that is converted by enzymes to NMN in the cells. As this pathway is safe and also the most efficient route for production of NAD, NMN or NR supplementation has been used to increase NAD levels.

Animal studies have shown that NMN supplementation can ameliorate the age-related reduction in NAD production in cells and improve the body's cardiovascular response to ageing. Age-related decrease in arterial elasticity means that the aorta is less able to expand and buffer the increased blood pressure generated each time the heart pumps. With ageing, the production of a pressure-bearing protein, type 1 collagen, in the arterial wall increases, whereas the main protein responsible for the structural integrity and elastic properties of the arterial wall, elastin, decreases. Studies in mice have shown that NMN supplementation was able to reduce stiffness in large arteries by reversing the accumulation of type 1 collagen in arterial walls and improving elastin content.

From the age of 40 years onwards, there is a gradual decline in perfusion of the body tissues resulting in gradual deterioration in body function towards the last decades of life. A consequence of this is cognitive decline.

Optimal brain function is dependent on adequate oxygen and nutrient delivery via minute brain blood vessels (cerebral microvascular circulation). This modulation of brain blood flow in response to increased brain activity is impaired with age, contributing to age-related cognitive impairment. Studies in aged mice given NMN have demonstrated an improvement in the modulation of cerebral microvascular circulation. Animal studies have also shown that NMN can prevent age-related cognitive decline by reducing cell death in areas of the brain that control short- and long-term memory.

Use of NMN was also associated with decrease in the neurodegenerative changes seen in Alzheimer's disease and age-related retinal changes. This age-related decrease in the production of new vessels and a gradual decrease of blood vessels in the microcirculation also result in reduction in muscle mass and diminishing exercise capacity with age. Mice given NMN were able to demonstrate an increase in the production of new vessels in the muscle and an increase in density of small vessels, thereby improving exercise capacity.

Caloric restriction

Caloric restriction (CR) which involves calorie reduction without causing malnutrition, has been associated with an increase in lifespan in some animal studies. In these studies, dietary CR was associated with increased lifespan and reduced disease incidence, especially cancers. However, some studies did not show benefit and, in some mouse strains, CR was associated with shortened lifespan.

Observational studies on humans who have practised extreme CR over many years showed low levels of risk factors for cardiovascular disease and diabetes.

Similarly, a human study on CR, the CALERIE study, found that CR participants had lower blood pressure and lower cholesterol.

The study was too short to examine the impact of CR on lifespan. The current conclusion from the National Institute of Aging in the United States is that there is not enough evidence to recommend CR as a therapeutic measure for life extension. Although CR was associated with lower risk factors for cardiovascular diseases and diabetes, caution is urged as in a study using mouse lemurs on prolonged CR, MRI studies showed that there was more widespread age-related grey matter atrophy in CR animals while only a few regions in the brain showed atrophy in those not on CR.

Life extension

Globally, heart disease and stroke are the two main causes of death in most high-middle and high-income countries. Hence, the first cardinal principle in life extension is to control the risk factors such as blood pressure elevation, cholesterol elevation, sugar elevation and smoking.

The second principle is to have a healthy lifestyle such as keeping the weight within the healthy range and exercising regularly. Both physical exercise and dietary CR result in a significant increase in NAD production and increase sirtuin activity. CR may be an option as part of a weight-reduction regime to keep the weight optimal.

The third principle is to see your doctor regularly to control risk factors.

Finally, among the supplement options, scientific studies favour the use of low-dose resveratrol or NMN as they may potentially provide many health benefits via increased sirtuin activity, although more studies will be required to understand their efficacy in human life extension.

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Life extension health, rejuvenation and longevity - The Business Times