The antibiotics-resistant superbug that emerged in South Asia appears to have claimed its first life. According to doctors who treated a man in Belgium, he went to a hospital in Pakistan after a car accident, and there he picked up the bacterial infection. While the man died back in June, his doctors announced today that he carried the superbug.
This new health scare intensified this week after researchers published a study in The Lancet Infectious Diseases characterizing “a new antibiotic resistance mechanism” in the U.K., India, and Pakistan. How bad is this “mechanism?”
It’s bad:
The problem isn’t a particular kind of bacteria. It’s a gene that encodes an enyzme called New Delhi metallo-lactamase-1 (NDM-1). Bacteria that carry it aren’t bothered by traditional antibiotics, or even the drugs known as carbapenems deployed against antibiotic-resistant microbes.
The NDM-1 gene is a special worry because it is found in plasmids — DNA structures that can easily be copied and then transferred promiscuously among different types of bacteria. These include Escherichia coli, the commonest cause of urinary tract infections, and Klebsiella pneumoniae, which causes lung and wound infections and is generated mainly in hospitals [AFP].
It’s no worse than what we had before:
Yes, NDM-1 is scary. But it’s not unprecedented.
There are numerous strains of antibiotic-resistant germs, and although they have killed many patients in hospitals and nursing homes, none have yet lived up to the “superbug” and “flesh-eating bacteria” hyperbole that greets the discovery of each new one. “They’re all bad,” said Dr. Martin J. Blaser, chairman of medicine at New York University Langone Medical Center. “Is NDM-1 more worrisome than MRSA? It’s too early to judge” [The New York Times].
The Los Angeles Times contends that the problem is not a serious problem for the West—at least not yet. The people in the most danger are patients in hospitals, The New York Times says—especially ones with weaker immune systems.
Could it happen anywhere?
India and Pakistan have developed some excellent hospitals and surgeons that provide medical care and surgical procedures, especially elective procedures, more cheaply than they are available in the West. But the overuse of antibiotics among the larger population leads to the development of resistance, and those organisms can make their way into even the best hospitals [Los Angeles Times].
Indians, however—cognizant of the bad press that comes with having a medical scare named after one’s capital city—have fought back against the idea that their practices brought on the emergence of a superbug.
“Several superbugs are surviving in nature and they have been reported from countries like Greece, Israel, the U.S., Britain, Brazil,” and elsewhere, V. M. Katoch, director general of the Indian Council of Medical Research in New Delhi told India Real Time. “It’s unfortunate that this new bug, which is an environmental thing, has been attached to a particular country” [Wall Street Journal].
Related Content:
DISCOVER: Promising Antibiotic Could Spawn the Next Superbug
80beats: Tiny Nanotech “Diving Boards” Test the Killing Power of Antibiotics
80beats: Non-Lethal Antibiotics Could Fight “Superbugs”
80beats: Red Meat Acts as Trojan Horse for Toxic Attacks By E. Coli
Image: USDA
- I Spy With My Little Eye… [Last Updated On: November 7th, 2009] [Originally Added On: November 7th, 2009]
- A Crack Opens in the Ethiopian Landscape, Preparing the Way for a New Sea | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- The Politics of Addiction | The Intersection [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Finally! An iPhone App That Lets You Track Your Bathroom Habits | Discoblog [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Don’t Pack Your Bags Yet—New Planet-Finder Hobbled by Electronic Glitch | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- In Controversial Scent Lineups, a Dog’s Nose Picks Out the Perp | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Are You a Cognitive Miser? | Cosmic Variance [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- The Secret Lives and Loves of Great White Sharks | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Britain’s New Protected Minority: Tree-Huggers | Discoblog [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Inspired by Maple Seeds, a Robotic Whirligig Takes To The Skies | Discoblog [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- New Statesman on Accommodationism | The Intersection [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Laser-Powered Robot Climbs to Victory in the Space-Elevator Contest | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Checking Back In With SEAPLEX | The Intersection [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Podcast: An Embarrassment of Genomes | The Loom [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- A Baby Neutron Star, Swaddled in a Carbon Atmosphere | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Butterfliiiies… iiinnnn… SPPPAAAAACCCCEEEEE! | Bad Astronomy [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- My Slate Dialogue with Michael Specter Begins | The Intersection [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Musical, Fahrvergnügen-Inspired Staircase Makes Commuters Less Lazy | Discoblog [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Laser-Etched Fruit Is an Answer in Search of a Problem | Discoblog [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Ares and the carnivals | Bad Astronomy [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Toddler Gets a Telescoping, Prosthetic Arm Bone That Grows With Him | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Neutered HIV Virus Delivers Treatment to Fatally Ill Boys | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Specter’s First Reply: Denialism Kills People | The Intersection [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- LRO sees a Moonslide | Bad Astronomy [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Al Gore’s New Book: A Focus on Solutions | The Intersection [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- The Universe Has Us in Its Crosshairs | Bad Astronomy [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Makers of Universes | Cosmic Variance [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Can Your Pet Catch & Spread Swine Flu? Yes, If Your Pet’s a Ferret | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Droid 2.0 Vs iPhone | The Intersection [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Tangled Bank News: An Excerpt and More | The Loom [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- LHC Shut Down By Wayward Baguette, Dropped by Bird Saboteur | Discoblog [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Careidolia | Bad Astronomy [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Slate Reply to Specter Up–We Need a National Dialogue on Synthetic Biology | The Intersection [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Pray this doesn’t get passed | Bad Astronomy [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- You Can’t Make This Stuff Up | Cosmic Variance [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Mother Tongue, Indeed: Newborn’s Cries Mimic Mama’s Accent | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Ripped From the Journals: The Biggest Discoveries of the Week | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Alternative Landscapes | The Loom [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Can an iPhone App Decipher Your Baby’s Cries? | Discoblog [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Reminder: Carl Sagan Day | Bad Astronomy [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Are There Pesticides in Your Soup? Dunk a Pollution Dipstick to Find Out. | 80beats [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Log in and Join the Conference [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Conference Ends [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Conference Archive Opens [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Galaxy Zoo [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- .Astronomy 2009 Dates [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- .Astronomy 2009: Programme and venue details [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- .Astronomy Gets Some IYA Love [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- 2009 Posters and Imagery [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- 2009 Sponsors [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- When in Holland… [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- The WHAT Cloud? [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- The Jewel Box [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Happy Halloween! [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Ares 1-X Launch [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Confessions of an Alien Hunter [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- LRO Spies Apollo 17 Site [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Mercury in Color [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Hubble and M83 [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Cassini Flyby of Enceladus [Last Updated On: November 8th, 2009] [Originally Added On: November 8th, 2009]
- Preserving A Moth [Science Tattoo] | The Loom [Last Updated On: December 12th, 2009] [Originally Added On: December 12th, 2009]
- Another Russian rocket spiral lights up the sky | Bad Astronomy [Last Updated On: December 12th, 2009] [Originally Added On: December 12th, 2009]
- A (Very Gentle) Riddle to Complete Your Saturday [Last Updated On: December 12th, 2009] [Originally Added On: December 12th, 2009]
- Darwin Gets Swine Flu: The YouTube Edition | The Loom [Last Updated On: December 12th, 2009] [Originally Added On: December 12th, 2009]
- Happy Slothy Holidays | The Loom [Last Updated On: December 12th, 2009] [Originally Added On: December 12th, 2009]
- Jetting to Copenhagen | The Intersection [Last Updated On: December 12th, 2009] [Originally Added On: December 12th, 2009]
- Michael Gerson Attempts Thoughtfulness on “ClimateGate,” Then Gives it Up | The Intersection [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Incredible VISTA of the cosmos | Bad Astronomy [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Bundle up Sunday Night to Watch the Geminid Meteor Shower | 80beats [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- “ClimateGate” a PR Disaster That Will Be “Taught in University Communications Courses” | The Intersection [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Is Google the Guardian Angel of Rainforests? | 80beats [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- La ciencia es importante. Una vez mas. | Bad Astronomy [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Sensenbrenner Pulls an Inhofe, Asserts Global Warming is an “International Conspiracy” | The Intersection [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Let Kids Eat Dirt: Over-Cleanliness Linked to Heart Disease | 80beats [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- What Are The Best Science Papers Of The Past Decade? | The Intersection [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Finally! Math Shows How to Cut Evenly Sized Pizza Slices | Discoblog [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Half-baked math | Bad Astronomy [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Can “Biological Passports” Save Sports From Doping? | 80beats [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Aiiiieeee! Slow down! | Bad Astronomy [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]
- Weekly News Roundup: Bad Headlines, Martian moons, and Rotating Houses | Discoblog [Last Updated On: December 13th, 2009] [Originally Added On: December 13th, 2009]