Healthy Longevity Initiative Grant Awarded to Study the Mycobiome as a Novel Class of Probiotics to Target Inflammaging
CAMBRIDGE, Mass., Nov. 4, 2021 /PRNewswire/ -- Solarea Bio, a biotechnology company in Cambridge, Mass., and leading researchers at Harvard Medical School affiliated Hebrew SeniorLife, New England's largest nonprofit provider of senior health care and living communities, are co-investigators on a competitive research grant from the U.S. National Academy of Medicine's Healthy Longevity Initiative.
(PRNewsfoto/Solarea Bio)
Solarea Bio, along with Douglas P. Kiel, M.D., M.P.H., Director, Musculoskeletal Research Center, Hinda and Arthur Marcus Institute for Aging Research, and Shivani Sahni, Ph.D., Director, Nutrition Program, Marcus Institute, received the grant.
According to the researchers, "An aging population has led to a significant global increase in age-related diseases including cardiovascular disease, Alzheimer's, and others. At the core of this is chronic low-grade inflammation known as inflammaging, and recent evidence describes the gut microbiome as a key regulator of the inflammaging process through direct impact on immune system development and function."
However, while the impact bacteria have on the immune system and human health is well described, fungi, a major component of the gut microbiome, have been largely overlooked due to multiple factors including fungi's large, complex genomes that require deep sequencing and a hybrid assembly, lack of fungal genome databases for functional gene prediction, and underdeveloped bioinformatic tools to identify fungal metabolites important to human health.
The researchers hypothesize that the "mycobiome" (the collection of fungi that are part of the overall microbiome) could offer a large, untapped reservoir of probiotic fungi with the ability to combat inflammaging. Based on this hypothesis, the team will be working to sequence a subset of a large fungal collection and develop bioinformatic tools to identify fungi with probiotic potential. Lead candidate fungi will be tested using in vitro cell culture systems to identify fungi with anti-inflammatory properties that may then be further tested clinically.
Story continues
About the Healthy Longevity InitiativeThe Healthy Longevity Initiative is designed to kick start innovation to support healthy longevity through a series of monetary awards and prizes. In the tradition of international races to fly across the Atlantic or walk on the moon, the initiative will rally the world's greatest minds to achieve what may at first seem an impossible goal.
About the Hinda and Arthur Marcus Institute for Aging ResearchScientists at the Marcus Institute seek to transform the human experience of aging by conducting research that will ensure a life of health, dignity, and productivity into advanced age. The Marcus Institute carries out rigorous studies that discover the mechanisms of age-related disease and disability; lead to the prevention, treatment, and cure of disease; advance the standard of care for older people; and inform public decision-making.
About Hebrew SeniorLifeHebrew SeniorLife, an affiliate of Harvard Medical School, is a national senior services leader uniquely dedicated to rethinking, researching, and redefining the possibilities of aging. Hebrew SeniorLife cares for more than 3,000 seniors a day across six campuses throughout Greater Boston. Our locations include: Hebrew Rehabilitation Center-Boston and Hebrew Rehabilitation Center-NewBridge in Dedham; NewBridge on the Charles, Dedham; Orchard Cove, Canton; Simon C. Fireman Community, Randolph; Center Communities of Brookline, Brookline; and Jack Satter House, Revere. Founded in 1903, Hebrew SeniorLife also conducts influential research into aging at the Hinda and Arthur Marcus Institute for Aging Research, which has a portfolio of more than $63 million, making it the largest gerontological research facility in the U.S. in a clinical setting. It also trains more than 1,000 geriatric care providers each year. For more information about Hebrew SeniorLife, visit https://www.hebrewseniorlife.org or follow us on our blog, Facebook, Instagram, Twitter, and LinkedIn.
About Solarea BioSolarea Bio is a biotechnology company based in Cambridge, Mass. developing new microbiome-based solutions to some of the world's largest health problems. Solarea was founded in 2017 by a group of scientists and entrepreneurs eager to radically alter our understanding of the human microbiome and utilize its power to improve human health. Solarea's breakthrough came from the combined efforts of the company's co-founders who established a link between the discovery of an untapped source of microorganisms with probiotic potential in healthy foods, and their applications in inflammatory processes including the gut-musculoskeletal axis.
Media Contacts:Margaret BonillaHebrew SeniorLife617-363-8367margaretbonilla@hsl.harvard.edu
Rachel Raymond Solarea Biorraymond@solareabio.com
Logo
Cision
View original content to download multimedia:https://www.prnewswire.com/news-releases/solarea-bio-teams-up-with-hebrew-seniorlife-investigators-on-a-newly-awarded-us-national-academy-of-medicine-catalyst-grant-301416424.html
SOURCE Solarea Bio
- Water Test Finds Toxic Substance [Last Updated On: August 17th, 2024] [Originally Added On: April 4th, 2010]
- Sunlight May Help Protect Men From Kidney Cancer [Last Updated On: August 17th, 2024] [Originally Added On: April 9th, 2010]
- Sunlight May Help Protect Men From Kidney Cancer [Last Updated On: April 10th, 2010] [Originally Added On: April 10th, 2010]
- Heart Disease [Last Updated On: August 17th, 2024] [Originally Added On: April 13th, 2010]
- Heart Disease [Last Updated On: April 14th, 2010] [Originally Added On: April 14th, 2010]
- The pH Miracle Living Diet Can Change Your Life [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2010]
- The pH Miracle Living Diet Can Change Your Life [Last Updated On: April 18th, 2010] [Originally Added On: April 18th, 2010]
- Garlic Good For Stomach and Colon Cancers [Last Updated On: August 17th, 2024] [Originally Added On: April 21st, 2010]
- Garlic Good For Stomach and Colon Cancers [Last Updated On: April 22nd, 2010] [Originally Added On: April 22nd, 2010]
- Smokeless tobacco products like snuff also cause cancer [Last Updated On: April 25th, 2010] [Originally Added On: April 25th, 2010]
- Smokeless tobacco products like snuff also cause cancer [Last Updated On: August 17th, 2024] [Originally Added On: April 26th, 2010]
- Prevention of Acupuncture Infection Needs More Focus [Last Updated On: April 29th, 2010] [Originally Added On: April 29th, 2010]
- Prevention of Acupuncture Infection Needs More Focus [Last Updated On: August 17th, 2024] [Originally Added On: April 30th, 2010]
- Squamous cell carcinoma and Epstein Bar [Last Updated On: May 3rd, 2010] [Originally Added On: May 3rd, 2010]
- Squamous cell carcinoma and Epstein Bar [Last Updated On: August 17th, 2024] [Originally Added On: May 4th, 2010]
- Prostate cancer therapy can increase risk of heart disease and death [Last Updated On: May 7th, 2010] [Originally Added On: May 7th, 2010]
- Prostate cancer therapy can increase risk of heart disease and death [Last Updated On: August 17th, 2024] [Originally Added On: May 8th, 2010]
- Protect Your Baby's Smile [Last Updated On: May 11th, 2010] [Originally Added On: May 11th, 2010]
- Protect Your Baby's Smile [Last Updated On: August 17th, 2024] [Originally Added On: May 12th, 2010]
- Acupuncture Seminar & Workshop (May 14-16, 2010, New York, New York, USA, North America) [Last Updated On: August 17th, 2024] [Originally Added On: May 14th, 2010]
- Acupuncture Seminar & Workshop (May 14-16, 2010, New York, New York, USA, North America) [Last Updated On: August 17th, 2024] [Originally Added On: May 14th, 2010]
- New Insights Show Ginseng Fights Inflammation [Last Updated On: May 15th, 2010] [Originally Added On: May 15th, 2010]
- Acupuncture Delivers Some Pain Relief [Last Updated On: May 19th, 2010] [Originally Added On: May 19th, 2010]
- Natural compounds in carnivorous plants could fight human fungal infections [Last Updated On: May 23rd, 2010] [Originally Added On: May 23rd, 2010]
- 12th National Conference: Parkinson's 2010: Recent clinical advances in the management of Parkinson's (Jun 23, 2010, London, United Kingdom, Europe) [Last Updated On: August 17th, 2024] [Originally Added On: May 23rd, 2010]
- 12th National Conference: Parkinson's 2010: Recent clinical advances in the management of Parkinson's (Jun 23, 2010, London, United Kingdom, Europe) [Last Updated On: August 17th, 2024] [Originally Added On: May 23rd, 2010]
- How to Treat Diabetes Without Medication [Last Updated On: May 27th, 2010] [Originally Added On: May 27th, 2010]
- How to Treat Diabetes Without Medication [Last Updated On: August 17th, 2024] [Originally Added On: May 28th, 2010]
- Testosterone May Make Women Less Trusting [Last Updated On: August 17th, 2024] [Originally Added On: June 2nd, 2010]
- Testosterone May Make Women Less Trusting [Last Updated On: June 3rd, 2010] [Originally Added On: June 3rd, 2010]
- Brain Develops Differently in Fragile X Syndrome [Last Updated On: August 17th, 2024] [Originally Added On: June 6th, 2010]
- Brain Develops Differently in Fragile X Syndrome [Last Updated On: June 7th, 2010] [Originally Added On: June 7th, 2010]
- Gaia Herbs achieves industry breakthrough in herb potency, safety and traceability [Last Updated On: August 17th, 2024] [Originally Added On: June 10th, 2010]
- Gaia Herbs achieves industry breakthrough in herb potency, safety and traceability [Last Updated On: June 11th, 2010] [Originally Added On: June 11th, 2010]
- Doctors are addicted to "every drug under the sun" [Last Updated On: August 17th, 2024] [Originally Added On: June 14th, 2010]
- Doctors are addicted to "every drug under the sun" [Last Updated On: June 15th, 2010] [Originally Added On: June 15th, 2010]
- Like Humans, Chimps Ape Their Betters [Last Updated On: August 17th, 2024] [Originally Added On: June 18th, 2010]
- Like Humans, Chimps Ape Their Betters [Last Updated On: June 19th, 2010] [Originally Added On: June 19th, 2010]
- Exercise in Adolescence May Cut Risk of Deadly Brain [Last Updated On: August 17th, 2024] [Originally Added On: June 22nd, 2010]
- Exercise in Adolescence May Cut Risk of Deadly Brain [Last Updated On: June 23rd, 2010] [Originally Added On: June 23rd, 2010]
- BP is burning rare sea turtles alive, blocking efforts to save them [Last Updated On: August 17th, 2024] [Originally Added On: June 26th, 2010]
- BP is burning rare sea turtles alive, blocking efforts to save them [Last Updated On: June 27th, 2010] [Originally Added On: June 27th, 2010]
- Exercise Helps Reduce Falls in Young and Old [Last Updated On: August 17th, 2024] [Originally Added On: June 30th, 2010]
- Exercise Helps Reduce Falls in Young and Old [Last Updated On: July 1st, 2010] [Originally Added On: July 1st, 2010]
- Scientists Spot Gene Variants That Predict Longevity [Last Updated On: July 7th, 2010] [Originally Added On: July 7th, 2010]
- Scientists Spot Gene Variants That Predict Longevity [Last Updated On: August 17th, 2024] [Originally Added On: July 8th, 2010]
- Mediterranean Diet Helps Protect Aging Brain [Last Updated On: July 11th, 2010] [Originally Added On: July 11th, 2010]
- Mediterranean Diet Helps Protect Aging Brain [Last Updated On: August 17th, 2024] [Originally Added On: July 12th, 2010]
- Diabetes Medicines [Last Updated On: July 15th, 2010] [Originally Added On: July 15th, 2010]
- Diabetes Medicines [Last Updated On: August 17th, 2024] [Originally Added On: July 16th, 2010]
- Cutting Calories May Boost Aging Brains [Last Updated On: July 23rd, 2010] [Originally Added On: July 23rd, 2010]
- Meditation Appears to Boost Attention Span [Last Updated On: July 31st, 2010] [Originally Added On: July 31st, 2010]
- Meditation Appears to Boost Attention Span [Last Updated On: August 17th, 2024] [Originally Added On: August 1st, 2010]
- A healthy heart slows brain aging [Last Updated On: August 17th, 2024] [Originally Added On: August 9th, 2010]
- Constipation May Lead to Other Problems [Last Updated On: August 12th, 2010] [Originally Added On: August 12th, 2010]
- A healthy heart slows brain aging [Last Updated On: August 12th, 2010] [Originally Added On: August 12th, 2010]
- 7-year-old girl dies after Botox injections [Last Updated On: August 16th, 2010] [Originally Added On: August 16th, 2010]
- Infidelity Rises When She Makes More Than He Does [Last Updated On: October 11th, 2010] [Originally Added On: October 11th, 2010]
- Confused About Coconut Oil? [Last Updated On: October 11th, 2010] [Originally Added On: October 11th, 2010]
- Widely Used Plastics Chemical Linked to Testosterone Boost [Last Updated On: October 11th, 2010] [Originally Added On: October 11th, 2010]
- Monitoring of Kidney Health Urged for Injection Drug Users [Last Updated On: October 11th, 2010] [Originally Added On: October 11th, 2010]
- A Stone-age prescription [Last Updated On: October 11th, 2010] [Originally Added On: October 11th, 2010]
- Researchers Reluctantly Admit Mediterranean Diet Beats Diabetes Drugs for Controlling [Last Updated On: October 11th, 2010] [Originally Added On: October 11th, 2010]
- Simplified Framingham Model May Miscalculate Risk for Millions [Last Updated On: October 11th, 2010] [Originally Added On: October 11th, 2010]
- New and Undefined Diseases [Last Updated On: October 11th, 2010] [Originally Added On: October 11th, 2010]
- Infidelity Rises When She Makes More Than He Does [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Confused About Coconut Oil? [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Widely Used Plastics Chemical Linked to Testosterone Boost [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Monitoring of Kidney Health Urged for Injection Drug Users [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- A Stone-age prescription [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Researchers Reluctantly Admit Mediterranean Diet Beats Diabetes Drugs for Controlling [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Simplified Framingham Model May Miscalculate Risk for Millions [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- New and Undefined Diseases [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- 7th Annual Update Symposium on Clinical Neurology & Neurophysiology (Feb. 21-22, 2011, Tel Aviv, Israel, Middle East) [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- 7th Annual Update Symposium on Clinical Neurology & Neurophysiology (Feb. 21-22, 2011, Tel Aviv, Israel, Middle East) [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- The 13th National Conference Dementias 2011 (Feb. 10-11, 2011, London, United Kingdom, Europe) [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Geriatrics: A Primary Care Approach to the Aging Population (Jan. 31-Feb. 04, 2011, Sarasota, Florida, USA, North America) [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- COSMODERM XIV - The International Aesthetic Dermatology Congress of the European Society for Cosmetic & Aesthetic Dermatology (ESCAD) (Dec 09-12, 2010, Dresden, Germany, Europe) [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- COSMODERM XIV - The International Aesthetic Dermatology Congress of the European Society for Cosmetic & Aesthetic Dermatology (ESCAD) (Dec 09-12, 2010, Dresden, Germany, Europe) [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Experimental Treatment Could Fight Muscular Dystrophy [Last Updated On: October 13th, 2010] [Originally Added On: October 13th, 2010]