Everyone knows that friendship is a key component ofGrey's Anatomy. For sixteen years, fans have had the pleasure of seeing these relationships blossom and grow. They loved watching the Twisted Sisters take Grey-Sloan by storm and seeing the epic bromance between Mark and Derek. They even loved the dynamic between Arizona and Webber, whose partnership came late in the game but was one for the ages.

RELATED: Grey's Anatomy: 10 Reasons Why Cristina & Callie Aren't Real Friends

However, with so many characters on the show, not all partnerships could progress to the friendship stage. A prime example: Callie Torres and Miranda Bailey's. Despite sharing many scenes, their characters didn't have the easiest relationships. Don't believe it? Keep reading to discover the 10 reasons why.

One reason why Bailey and Callie couldn't be friends was their opposing personalities. Most of the time, Bailey is seen as a very strict and private person. She likes to maintain a professional boundary with her colleagues and is never seen engaging in hospital gossip or consorting with them at Joe's.

On the other hand, Callie can be seen as Baileys character foil. She is outgoing, relaxed, and open-minded. Despite her tough exterior, Callie has also been shown to wear her heart on her sleeve. Based on these differences, Bailey and Callie tend to associate with different social circles, meaning their friendship would always be weak.

Another moment that proved why Callie and Bailey weren't real friends was when Callie laughed in the general surgeon's face when she confided in her. As mentioned, Bailey is a very private person and hardly talks about her personal life. When she did, it was mainly about something that made her feel vulnerable.

For instance, in "The End is the Beginning," Bailey confided in Callie about an incident on her honeymoon that left her seriously embarrassed. Instead of reassuring her or offering advice, Callie just laughs at Bailey's misery. It's not exactly the reaction you would want from a trusted friend especially if you are feeling insecure.

In season 4, a bitter rivalry formed between Callie and Bailey after they competed to become Chief Resident. Bailey believed she was a shoo-in for the role since she was the Chief's favorite and highly respected among the staff. However, after spending months battling it out, Bailey was surprised when Webber announced he had given the role to Callie.

RELATED: Grey's Anatomy: Why Alex And Arizona Aren't Real Friends

Instead of being pleased for Callie, Bailey could only express her disappointment over the loss. She then refused to speak to Webber over his decision. If Callie was really her friend, Bailey would have been happy and congratulated her instead of acting like a petulant child.

Bailey continued to act immaturely when she undermined Callie's authority in front of the Chief and the residents. In "A Change is Gonna Come," Callie's role as Chief Resident didn't get off to the best start when the other surgeons failed to answer her pages.

When Webber asks Callie why M.A.G.I.C. was ignoring her, Bailey sniped about how they "always came running" for her. Callie also gets annoyed when the residents go over her head to Bailey when they disagree with her decisions. Instead of supporting her, Bailey continued to humiliate Callie by disrespecting her in front of their colleagues. It's not something a good friend would do.

In "Run, Baby, Run," Bailey was seen to be preparing for her second wedding and asked Callie if she would be a bridesmaid. However, Callie wasn't exactly the ideal candidate when she advises Bailey to run aftershe expressed that she's having doubts.

RELATED: Grey's Anatomy: Why Meredith & Cristina Aren't Real Friends

Callie also suggested that she should leave Ben at the altar because marriage was like "a dance of death." Considering that she was meant to be Bailey's maid of honor, Callie was doing a terrible job of it. If she knew Bailey, Callie would have known the general surgeon didn't joke in stressful situations. It's just another moment that proves they weren't real friends.

When it came to love, Callie didn't have the best of luck in that department. Her first marriage to George collapsed after the intern left her for his best friend, Izzie. Her second marriage was also broken beyond repair when Arizona had a one-night stand with another surgeon.

Did Bailey check in on Callie to see if she was okay? Nope on both occasions, Bailey was nowhere to be seen. It's not as if she could remain oblivious to the infidelities, either, as she was in the room when Arizona's unfaithfulness was uncovered. At a time like this, friends usually rally with support. Yet Bailey didn't, which showsshe and Callie aren't close enough to be considered friends.

Once more, Callie proved to be the world's worst maid of honor and friend when she failed to turn up to Bailey's wedding. After Adele was admitted to the hospital, Ben decided to open the reception first while they waited on Bailey to finish operating.

RELATED: Grey's Anatomy: 10 Reasons Why Mark & Derek Aren't Real Friends

Instead of waiting with the other guests, Callie and Arizona decided to get a room at the hotel. However, it appears they lose track of time because they fail to turn up at the wedding, sneaking into the reception after everything is finished. The fact that Callie let Bailey down and had no qualms about it proved they weren't very good friends.

Near the end of season 9, Bailey's career was placed in jeopardy after three of her patients died contracting a staph infection. The hospital board decides the best way to get to the bottom was to get the CDC to investigate before a scandal broke ("Sleeping Monster"). However, the board including Calliedidn't exactly treat Bailey in the best manner.

RELATED: Grey's Anatomy: 5 Best Friendships (& 5 Worst)

For instance, when the accusations first come to light, Callie just stands back and lets them treat Bailey like a pariah. When the CDC arrives, Callie also avoids Bailey and refuses to talk to her until the investigation is over. Callie knew that Bailey would have been terrified, yet she did nothing to help ease her fears. Once again, it proved Calliewasn't someone Bailey could rely on.

In season 12, a huge storyline was put in motion when Arizona took Callie to court to try and get custody of Sofia. This all came to a head in "Mama Tried," where several members of the hospital testified on behalf of the two women including Bailey.

Bailey was there to be a character witness for both women and was trying to do her best to be impartial. However, Callie ends up making it personal when she allows her lawyer to ask Bailey questions that would assassinate Arizona's character. Not did it put Bailey in an uncomfortable position, but it also jeopardized Bailey's relationship with Arizona. A friend would never put someone on the spot like this.

Since Callie placed Bailey on the spot, it wasn't surprising when the Chief ended up fighting back and defending Arizona. As Callie's lawyer attempted to make Arizona look like a workaholic, Bailey sniped how the fetal surgeon has a very successful and high-demanding career, which doesn't make her a bad parent.

As Bailey continued to defend Arizona, she let Callie know that she isn't happy with the way she was handling the case. The fact that Bailey also didn't add anything to support Callie showed her allegiance swaying more towards Arizona. If Bailey refused to give a solid testimony in favor of Callie then they couldn't be deemed real friends.

NEXT: Grey's Anatomy: Most Heartbreaking Deaths, Ranked

Next10 Shows To Watch If You Like The Big Bang Theory

A writer, reader and tv fanatic, Kayleigh enjoys reading movie news and your film reviews. She has attained an Undergraduate degree in Creative Writing and is also the creator of the film and television blog 'The Critics' Corner'.

View post:
Grey's Anatomy: Why Miranda & Callie Aren't Real Friends - Screen Rant