He added: As I move on from Greys Anatomy, I want to thank the ABC family, Shonda Rhimes, original cast members Ellen Pompeo, Chandra Wilson and James Pickens, and the rest of the amazing cast and crew, both past and present, and, of course, the fans for an extraordinary ride.

In a number of letters sent to loved ones including his wife Dr Jo Wilson (Camilla Luddington) and lifelong friend Meredith Grey (Ellen Pompeo), he said he was back in touch with ex-wife Dr Izzie Stevens (Katherine Heigl).

They had got back in touch after Meredith was on trial for insurance fraud and during their conversations, he discovered there was something she hadnt told him.

Before she left the series, Izzie had cancer and so, just in case she couldnt have children one day, her and Alex froze embryos and when she left the hospital, decided to use them.

The pair had twin five-year-old children together so he opted in to stay with his new family on a farm in Kansas, leaving his wife and the hospital behind.

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Greys Anatomy season 17: Is Greys Anatomy coming to an end? One star thinks so - Express