01.08.2012 - (idw) Goethe-Universitt Frankfurt am Main

Ivan Dikic will receive the William C. Rose Award 2013 FRANKFURT. Prof. Ivan Dikic, Head of the Institute of Biochemistry II and Director of the Buchmann Institute of Molecular Life Sciences at the Goethe University Frankfurt, was awarded with the William C. Rose Award 2013, as announced today by the American Society for Biochemistry and Molecular Biology.

With this Award, the American Society for Biochemistry and Molecular Biology recognizes outstanding contributions of Ivan Dikic to biochemical and molecular biological research and in particular his pioneering work in understanding the Ubiquitin Code that regulates multiple biological processes. The Award consists of a plaque and 3.000 US$ and will the awarded at the Annual Meeting in Spring, 2013, where Prof. DIkic will be invited to present his research.

Ivan Dikic has been working at the Medical Faculty of the Goethe University in Frankfurt since 2002. More then 10 years ago, he started to concentrate his work on the Ubiquitin Research. Prof. Dikic showed that Ubiquitin acts as a multivalent cellular signal recognized by an expanding number of binding proteins that in turn translate this molecular signal into appropriate cellular phenotypes. His group have identified several novel Ubiquitin binding domains and used structural and functional studies to demonstrate their roles in the regulation of DNA repair, inflammation, receptor endocytosis, and proteasomal degradation. Despite their biological relevance, modern-day tools to study Ub chains in their physiological environment remain rudimentary and mainly focus on the biochemical characterization of chains, substrates or ubiquitin-binding domains (UBDs). Lately, Ivan Dikics group described the development and in vivo application of highly versatile chain-specific Ub sensors.

Informations: Prof. Ivan Dikic, Institut fr Biochemie II and Buchmann Institute for Molecular Lifesciences, Campus Niederrad, Tel.: (069) 6301-5652; ivan.dikic@biochem2.de function fbs_click() {u=location.href;t=document.title;window.open('http://www.facebook.com/sharer.php?u='+encodeURIComponent(u)+'&t='+encodeURIComponent(t),'sharer','toolbar=0,status=0,width=626,height=436');return false;} html .fb_share_link { padding:2px 0 0 20px; height:16px; background:url(http://static.ak.facebook.com/images/share/facebook_share_icon.gif?6:26981) no-repeat top left; } Share on Facebook Weitere Informationen: http://www2.uni-frankfurt.de/42409151/038

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American Society for Biochemistry and Molecular Biology honors outstanding Scientists