Bruce Linton Talks Psychedelics Investments, Microdosing And LSD: ‘The Therapeutic Potential Of Psychedelics Is Greater Than Cannabinoids’ – Benzinga

Earlier this year, Canopy Growth (NYSE: CGC) co-founder and former CEO Bruce Linton invested in a neuropharmaceutical company, Mind Medicine Inc.

MindMed is a psychedelicresearch company thats developing non-hallucinogenic medicine from psychedelic sources. The company has also welcomed Linton to its board of directors.

The 53-year-old entrepreneur told Benzinga heplans to spend 2020 searching for new business ideas andwill start a new business in 2021.

Linton has long found the psychedelics sector to be compelling, Linton said.

Prohibition or poor regulatory frameworks globallydon't mean that the underlying regulated substances are in fact terrible. The therapeutic potential of psychedelics is greater than cannabinoids, for sure.

Supporting a company developing psychedelic substances for medicinal purposes is the best way to rediscover the therapeutic potential of certain plants and mushrooms that have long been banned by the FDA, he said.

"The whole point of this exercise is to build a large platform company that welcomes many, many research projects ... and turns them into finished outcomes that create therapeutic benefit," Linton said in reference to his involvement with Mind Medicine.

Once the therapeutic properties of psychedelics in treating conditions like ADHD, opioid addiction and severe depression are acknowledged, their histories of prohibition will be irrelevant, the cannabis exec said.

In that sense, the process for legalizing these substances is similar tocannabis, he said: achange in public perception is the main tool in fighting prohibition.

"At the end of the day, we're having the same conversation, with the same cohort."

See Also: The Keys To Understanding Psilocybin's Medical Value, Market Potential

Mind Medicine is researching the psychiatric potential of LSD and 18-MC, a synthesized version of ibogaine that is showing promising results in the treatment of opioid addiction.

The company recently raised $6.2 million to conduct Phase 2 clinical trials of18-MC.

Kevin OLeary, co-host of ABCs "Shark Tank," is among the companys investors.

Benzinga spoke with Mind Medicine co-founder and director JR Rahn.

Rahn, who has a tech background, decided to focus his entrepreneurial efforts on psychedelics after seeing many of his Silicon Valley colleagues microdosing LSD and other psychedelic compounds to increase focus and performance.

After researching the environment, Rahn said he decided to focus on the 18-MC molecule because of its promisein treating opioid addiction.

In 2013, the National Institute on Drug Abuse awarded a $6.7-million research grant to a pharmaceutical research company, Savant, to subsidize preclinical development of 18-MC for the treatment of obesity and substance use disorders.

Mind Medicine sprouted from Savant, Rahn said.

I co-founded the company with the Savant CEO. Savant sold the 18-MC program to MindMed in a share deal. Savants entire team has joined MindMed and is 100% focused on MindMed now. We used that money to do all this preclinical work and conduct a Phase 1 trial in humans to demonstrate that it was safe.

Rahn said his company aims to go public on Canadas NEO exchange in the first quarter of 2020, although the details are definitive.

The Benzinga Cannabis Capital Conference is heading to Miami Feb. 24-25 for its sixth installment.Click hereto learn more.

In recent years, psilocybinthe psychedelic molecule derived from magic mushroomshas been shaping up to be thestar compound in the psychedelic revolution of psychiatric treatment.

Psilocybin research is paving the way to psychedelic treatment in general and the development of psychedelics as an industry, Rahn said.

Yet hes placing his trust in the possibilities offered by 18-MC as a non-hallucinogenic psychedelic taken in microdoses.

Linton also commented on psilocybins commercial value.

The path to commercialization for the compound is financially unclear and difficult, he said. In Linton's view, commercial success relies on the possibility of modifying the original compounds.

"It's a very difficult molecule to alter. But there are a variety of other psychedelics that can be amended structurally to reduce their hallucinogenic effect, or they can actually have dose metering technologies that allow for well-structured delivery," he said.

"That to me gets to be very interesting commercially."

The definition of microdosing has yet to be standardized.

One approach would be to consider a "micro" dose of psychedelics to be one that's so low a hallucinogenic effect cannot be perceived, yet a therapuetic effect is achieved.

Yet as multiple scholars stated in a review paper on the subject, "there is no agreed scientific consensus on what microdosing is."

Linton is well aware of this fact.

"Whats micro?" he asks rhetorically. "How are you actually managing the dose? What's the frequency on micro? What are the primary indications that you're using it against? And what's the baseline of efficacy compared to other medicines? All that work is undone."

For Linton, the lack of knowledge on the subjectis more of an opportunity than a drawback.

"That means this is a bad idea currently because we have to do the work to show thats a great idea. If it was already a great idea, that means everybody did all the work. Im a big fan of investing in bad ideas."

Microdosing psychedelics offers vast potential not only in substance addiction, but also in the treatment of anxietyand adult ADHD.

The theory that this type of treatment can be dangerous to the heart especially using substances like LSD and 18-MC is unproven, Rahntold Benzinga.

"One of the things that well be doing is rigorous science and a Phase 2 clinical trial to demonstrate if there are issues relating to the heart or not. Because there aretheories that it might but there's been very little rigorous science on the microdosing subject."

See Also: Bruce Linton On His Next Steps, Says 'I'm Cheering For Entrepreneurs'

The pharmaceutical industry will be especially interested in psychedelics, Linton said.

Pharmaceutical companies need a pipeline of drugs that address mental health conditions and addiction, he said.

Rahn said there's a lack of investment in addiction medicine.

"On the opioid market, theres Suboxone. There are studies that demonstrate that it has a 90% failure rate. That's not good. We're not going to solve the opioid crisis that way."

For Linton, the debate around whether psychedelics have an effective impact on humans is no longer relevant.

"Humans have been using [psychedelics] for 3,000 or 4,000 years. Listen, if you don't think it does have an effect, then please go have an acid trip and tell me how it didn't affect you, he said. What I want to know is what amount, in what way, to get what outcome?"

Featured photo by Robina Weermeijer viaUnsplash.

2019 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

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Bruce Linton Talks Psychedelics Investments, Microdosing And LSD: 'The Therapeutic Potential Of Psychedelics Is Greater Than Cannabinoids' - Benzinga

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