Ask Dr. H: Is DNA passed from a blood donor

Whole blood contains not only red blood cells, but also other components like serum, white blood cells, platelets, and antibodies. It is the white blood cell component of whole blood that contains the nuclei and therein one's genetic material in the form of DNA.

However, even if one received a whole-blood transfusion rather than the red blood cells alone, the DNA profile of a donor would not be detected in the peripheral blood of a recipient.

In one study, a woman in a trauma situation was transfused with 14 units of blood (four of those units being whole blood) without showing any detectable level of foreign DNA. In another study, a man in a trauma situation received 13 units of blood (four of those units being whole blood) without showing any detectable level of the donor's DNA. That's a lot of blood they received, considering that the average woman has 8 to 10 pints/units of whole blood and the average man has 10 to 12 pints/units of blood.

Question:I've been taking Nexium for several years to treat Barrett's esophagus. I have heard that long-term use of acid-blocking drugs like Nexium can increase the risk of pneumonia. Why would it cause that? How much of a risk is it for me?

Answer:The timing of your question is superb, because a recent retrospective study conducted by researchers at the Massachusetts General Hospital Department of Medicine poked huge holes in the conclusion of previous studies linking chronic use of proton pump inhibitors (PPIs) like Nexium and Prilosec to a roughly 1 percent per-year increased risk of developing pneumonia.

The widely held belief has been that suppressing stomach acid can allow the growth of ingested bacteria to increase the risk of pneumonia. The belief is so strong that the FDA has issued warnings over it.

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Ask Dr. H: Is DNA passed from a blood donor

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