Shinya Yamanaka

Shinya Yamanaka, MD, PhD, is the fifth UCSF scientist to win the Nobel Prize in Physiology or Medicine.

Yamanaka is a busy man. He is a senior investigator and the L.K. Whittier Foundation Investigator in Stem Cell Biology at the Gladstone Institute of Cardiovascular Disease, a professor of anatomy at UCSF, director of the Center for iPS Cell Research and Application (CiRA) and a principal investigator at the Institute for Integrated Cell-Material Sciences (iCeMS), both at Kyoto University, Japan.

Other UCSF Nobel Prize winners include:

Elizabeth Blackburn

Elizabeth H. Blackburn, PhD, received the 2009 Nobel Prize in Physiology or Medicine. She shared the award with Carol W. Greider of Johns Hopkins University School of Medicine and Jack W. Szostak of Harvard Medical School. The scientists discovered an enzyme that plays a key role in normal cell function, as well as in cell aging and most cancers. The enzyme is called telomerase and it produces tiny units of DNA that seal off the ends of chromosomes, which contain the bodys genes. These DNA units named telomeres protect the integrity of the genes and maintain chromosomal stability and accurate cell division. They also determine the number of times a cell divides and thus determine the lifespan of cells.

The scientists research sparked a whole field of inquiry into the possibility that telomerase could be reactivated to treat such age-related diseases as blindness, cardiovascular disease and neurodegenerative diseases, and deactivated to treat cancer, in which it generally is overactive. Read more.

Stanley Prusiner

Stanley B. Prusiner, MD, received the 1997 Nobel Prize in Physiology or Medicine for his discovery of a novel disease-causing agent a protein he named prion (PREE-on). The prion causes rare neurodegenerative diseases, such as Creutzfeldt Jakob disease in humans, and mad cow disease in cattle. The discovery has informed research into the role of misprocessed proteins in more common brain diseases, including Alzheimers disease and Parkinsons disease.

J. Michael Bishop

The rest is here:
UCSF Nobel Prize Winners