If you feel youre too short or too tall you can blame your genes. And it looks like theres plenty of blame to go around.
A study in Naturehas identified dozens of infrequently occurring genetic variants that are associated with human height to a moderate or large degree, some of them carrying an influence of up to 2 centimeters (more than of an inch). A number of the DNA elements are tied to genes already known to affect growth, such as those affecting bones and hormones, but others represent new processes involved in growth and height. That latter group could potentially lead scientists to new treatments for growth disorders.
Read: Technology To Change Genes Could End Tuberculosis
In the context of precision medicine, the results also bring hope to understand the genetic basis of complex diseases such as diabetes or schizophrenia, according to the Swiss Institute of Bioinformatics. The idea is that if we can understand the genetics of a simple human trait like height, we could then apply this knowledge to develop tools to predict complex human diseases, researcher Zoltn Kutalik said in the institutes statement.
According to SIB, the research relied on the international effort of more than 300 scientists and pulled DNA data from more than 700,000 people.
Your body might contain genes that can add up to 2 centimeters to your height. Pixabay, public domain
While previous research has fingered hundreds of genetic variants for playing a role in height, the Nature study notes that those variants are much more common, butplay only a marginal role in a persons measurement. The newly discovered variants have greater than 10 times the average effect of common variants.
While DNA plays the biggest role in how tall we are, our diet and our environment also influence how we measure up. For instance, Scientific Americannotes that protein is the most important nutrient for final height. Minerals such as calcium, vitamin A and vitamin D are also significant. Because of this, malnutrition in childhood is detrimental to height.
Source: Marouli E, Graff M, Medina-Gomez C, et al. Rare and low-frequency coding variants alter human adult height. Nature. 2017.
See also:
Genes Tell Us Whether Youll Drop Out of School
How a Blood Transfusion Changes Your DNA
How Evolution Will Change Our Bodies
Read more from the original source:
Why You Are Short (Or Tall): Human Genetics, Explained - Medical Daily
- June 11th At Westport, CT: Federal Red Flags, HIPAA Security Rules and Fraud Prevention [Last Updated On: November 7th, 2009] [Originally Added On: November 7th, 2009]
- Do not learn Dvorak! [Last Updated On: November 7th, 2009] [Originally Added On: November 7th, 2009]
- You Can’t Solve Problems By Making It Illegal To Have The Problem [Last Updated On: November 7th, 2009] [Originally Added On: November 7th, 2009]
- A Force Fix for Healthcare [Last Updated On: November 7th, 2009] [Originally Added On: November 7th, 2009]
- Yahble, HIT, Bubblecon, BIZDEV!, Solid State [Last Updated On: November 7th, 2009] [Originally Added On: November 7th, 2009]
- 15 things that suck about the Palm Pre [Last Updated On: November 7th, 2009] [Originally Added On: November 7th, 2009]
- What an Indie Genomics Lab Looks Like [Last Updated On: November 7th, 2009] [Originally Added On: November 7th, 2009]
- Practice Fusion: Class D Felony? [Last Updated On: February 26th, 2010] [Originally Added On: February 26th, 2010]
- Practice Fusion Responds [Last Updated On: March 7th, 2010] [Originally Added On: March 7th, 2010]
- Practice Fusion: Do the math: $44,000 is a LIE [Last Updated On: March 10th, 2010] [Originally Added On: March 10th, 2010]
- How Much Until Doctors Approve of 23andMe? [Last Updated On: March 10th, 2010] [Originally Added On: March 10th, 2010]
- Biochemicals as Media, Not Methods [Last Updated On: March 10th, 2010] [Originally Added On: March 10th, 2010]
- More Practice Fusion Reality Distortion [Last Updated On: March 10th, 2010] [Originally Added On: March 10th, 2010]
- Same Test Results: 23andMe is Myriad is BRCA is Medicine [Last Updated On: March 12th, 2010] [Originally Added On: March 12th, 2010]
- BRCA is 23andMe is Myriad is Medicine [Last Updated On: March 13th, 2010] [Originally Added On: March 13th, 2010]
- Getting Serious About Genomics as Common Medical Practice [Last Updated On: March 15th, 2010] [Originally Added On: March 15th, 2010]
- The New John Mackey of Genetics: Linda Avey? [Last Updated On: March 15th, 2010] [Originally Added On: March 15th, 2010]
- Keep the Medical, Well, Medical [Last Updated On: March 16th, 2010] [Originally Added On: March 16th, 2010]
- If 23andMe shuts down, it won’t be for some mundane reason like the bills weren’t paid [Last Updated On: March 16th, 2010] [Originally Added On: March 16th, 2010]
- If I Run A Medical Practice, How Do I Use A 23andMe? [Last Updated On: March 17th, 2010] [Originally Added On: March 17th, 2010]
- 23andMe Contract in Bad Faith [Last Updated On: March 19th, 2010] [Originally Added On: March 19th, 2010]
- Doctors CANNOT Use 23andMe Due To 23andMe’s Bad Faith Contract [Last Updated On: March 20th, 2010] [Originally Added On: March 20th, 2010]
- Pathway Compared to 23andMe and Navigenics [Last Updated On: March 22nd, 2010] [Originally Added On: March 22nd, 2010]
- There’s a Word for “Views Differ” When One View Is The State [Last Updated On: March 24th, 2010] [Originally Added On: March 24th, 2010]
- Association for Molecular Pathology, et al. v. USPTO, et al. – Opinion [Last Updated On: March 29th, 2010] [Originally Added On: March 29th, 2010]
- Birth of a Super Villain [Last Updated On: April 3rd, 2010] [Originally Added On: April 3rd, 2010]
- “Medical Products” like 23andMe must not become the new “Financial Products” [Last Updated On: April 4th, 2010] [Originally Added On: April 4th, 2010]
- How I Would Apply Genomic Technology In Clinical Use Today [Last Updated On: April 5th, 2010] [Originally Added On: April 5th, 2010]
- Gmail Enterprise: World’s Best EMR [Last Updated On: April 6th, 2010] [Originally Added On: April 6th, 2010]
- Brief Primer on Health Law Compliance [Last Updated On: April 9th, 2010] [Originally Added On: April 9th, 2010]
- Spoiler: You ARE the “Valids” [Last Updated On: April 9th, 2010] [Originally Added On: April 9th, 2010]
- Rachel Lehmann-Haupt Line by Line Take Down [Last Updated On: April 9th, 2010] [Originally Added On: April 9th, 2010]
- Is Medicare Bankrupt? What the Hell Is Going On? [Last Updated On: April 17th, 2010] [Originally Added On: April 17th, 2010]
- The Big Shuffle: Medicare Cuts Rates by 21.3% (but not “technically”) [Last Updated On: April 17th, 2010] [Originally Added On: April 17th, 2010]
- “Tech Hiring Binge” == “Fear for Your Job, Nerds” [Last Updated On: April 18th, 2010] [Originally Added On: April 18th, 2010]
- How Bad is Bad? $.20 on the Private Medical Insurance Dollar [Last Updated On: April 20th, 2010] [Originally Added On: April 20th, 2010]
- Update: How Bad is Bad? It Used to Be $.45 on the Medical Insurance Dollar [Last Updated On: April 20th, 2010] [Originally Added On: April 20th, 2010]
- World’s Best “EMR” for $1000: Google Spreadsheets + iPad [Last Updated On: April 21st, 2010] [Originally Added On: April 21st, 2010]
- Don’t Insult Me with your “AOL Keyword” Strategy, Google Health [Last Updated On: April 21st, 2010] [Originally Added On: April 21st, 2010]
- How to Play LAWGAMES [Last Updated On: April 23rd, 2010] [Originally Added On: April 23rd, 2010]
- Top 4 Predatory Schemes Encroaching on American Medicine: Part 1 [Last Updated On: April 25th, 2010] [Originally Added On: April 25th, 2010]
- What’s the Big Deal About iPads? [Last Updated On: April 27th, 2010] [Originally Added On: April 27th, 2010]
- Got Google Android for Google I/O [Last Updated On: April 27th, 2010] [Originally Added On: April 27th, 2010]
- Google Enterprise meets HIPAA and HITECH Compliant Laws [Last Updated On: April 29th, 2010] [Originally Added On: April 29th, 2010]
- Pixels of Accuracy CHALENGE: Diagnostic Medical Imaging [Last Updated On: April 29th, 2010] [Originally Added On: April 29th, 2010]
- 23andMe Launder AlioGenetics Doesn’t Even Bother to Remove 23andMe Logo [Last Updated On: April 30th, 2010] [Originally Added On: April 30th, 2010]
- Anthem of CT Denies $600 Until “Subscriber Responds to our Coordination of Benefits Questionnaire” [Last Updated On: May 1st, 2010] [Originally Added On: May 1st, 2010]
- Apple And Google Team Up To Launch Revolutionary Mobile Health System [Last Updated On: May 1st, 2010] [Originally Added On: May 1st, 2010]
- Funny Pictures from This Year Building the Medical Practice [Last Updated On: May 6th, 2010] [Originally Added On: May 6th, 2010]
- Remote Medical Video Monitoring on iPad and iPhone [Last Updated On: May 7th, 2010] [Originally Added On: May 7th, 2010]
- Google Calendar Overhead Waiting Room Display [Last Updated On: May 7th, 2010] [Originally Added On: May 7th, 2010]
- Various Whiteboards on Solid State Medical Operations [Last Updated On: May 7th, 2010] [Originally Added On: May 7th, 2010]
- The Raw Facts about Counsyl [Last Updated On: May 7th, 2010] [Originally Added On: May 7th, 2010]
- Brawndo: Still Mutilating Thirst, Still Not Yet Sold at the Stop-n-Shop Pharmacy [Last Updated On: May 9th, 2010] [Originally Added On: May 9th, 2010]
- Video: Google Enterprise to Outsource Medical Administration [Last Updated On: May 9th, 2010] [Originally Added On: May 9th, 2010]
- Gattaca: “The Matrix” of Genomics [Last Updated On: May 11th, 2010] [Originally Added On: May 11th, 2010]
- 23andMe Now Diagnoses Fatal Tay-Sachs Disease [Last Updated On: May 12th, 2010] [Originally Added On: May 12th, 2010]
- Why Was Pathway Targeted for FDA Enforcement and Not 23andMe? [Last Updated On: May 15th, 2010] [Originally Added On: May 15th, 2010]
- John Dolan on Aging and the Horrifying Conclusion of GWAS [Last Updated On: May 16th, 2010] [Originally Added On: May 16th, 2010]
- Sam R. Riley Wants To Tell You About Practice Fusion [Last Updated On: May 17th, 2010] [Originally Added On: May 17th, 2010]
- Response to “Genomic Medicine: Lost” [Last Updated On: May 19th, 2010] [Originally Added On: May 19th, 2010]
- Death And Taxes: CMS to IRS [Last Updated On: May 19th, 2010] [Originally Added On: May 19th, 2010]
- Please Stop Antagonizing the AMA [Last Updated On: May 26th, 2010] [Originally Added On: May 26th, 2010]
- Dan Vorhaus, Attorney At Law, Legally Advises Medical Doctors Can Use 23andMe To Provide Medical Advice [Last Updated On: May 28th, 2010] [Originally Added On: May 28th, 2010]
- Singularity Summit 2010 in San Francisco to Explore Intelligence Augmentation [Last Updated On: June 7th, 2010] [Originally Added On: June 7th, 2010]
- OpenPCR: DNA amplification for anyone [Last Updated On: June 10th, 2010] [Originally Added On: June 10th, 2010]
- FDA sends letters to 5 genetic testing companies [Last Updated On: June 11th, 2010] [Originally Added On: June 11th, 2010]
- Amazon And The NIH Team Up To Put Human Genome In The Cloud [Last Updated On: March 31st, 2012] [Originally Added On: March 31st, 2012]
- ReproSource Comments on New Study Linking Infertility to Genetics [Last Updated On: April 25th, 2012] [Originally Added On: April 25th, 2012]
- Genetics 101 Part 1: What are genes? - Video [Last Updated On: April 30th, 2012] [Originally Added On: April 30th, 2012]
- Red Ice Radio - David Icke - Hour 1 - The Manipulation of Humanity - Video [Last Updated On: April 30th, 2012] [Originally Added On: April 30th, 2012]
- Genetics Part 5: Human Genetic Disorders - Video [Last Updated On: April 30th, 2012] [Originally Added On: April 30th, 2012]
- C2CAM - The Nephilim, Genetic Manipulation [Last Updated On: April 30th, 2012] [Originally Added On: April 30th, 2012]
- Human Nature talk with Robert Sapolsky, Gabor Mate, James Gilligan, Richard Wilkinson - Video [Last Updated On: April 30th, 2012] [Originally Added On: April 30th, 2012]
- Human Genetic Diseases - Video [Last Updated On: April 30th, 2012] [Originally Added On: April 30th, 2012]
- Alien Scientist on Genetics, Implants [Last Updated On: April 30th, 2012] [Originally Added On: April 30th, 2012]
- Research and Markets: Genetics, 6th Edition International Student Version Continues To Educate Today's Students for ... [Last Updated On: May 4th, 2012] [Originally Added On: May 4th, 2012]
- Myriad Genetics to Present at the Bank of America Merrill Lynch 2012 Health Care Conference [Last Updated On: May 4th, 2012] [Originally Added On: May 4th, 2012]
- Genetics may explain some people's dislike of meat [Last Updated On: May 4th, 2012] [Originally Added On: May 4th, 2012]
- 'Blond Genes' May Vary Around the World [Last Updated On: May 4th, 2012] [Originally Added On: May 4th, 2012]