The best hospitals in the world must deal with a plethora of challenges facing the health care field today, including tight regulations, rapid advancements in medical science, new health risks and ever-rising costs. And they must do so while also delivering on what must be a medical facility's No. 1 priority: providing top-notch patient care.

What is critical for health care consumers to figure out: Where can you find these industry leaders todaythe ones that meet the economic, political and medical challenges they face with speed and skill, while also providing the very best health care to the people they treat?

To help answer that question, Newsweek partnered with Statista Inc., a global market research and consumer data company, to develop a groundbreaking ranking of the world's best hospitals. The result is our second annual ranking of the best hospitals in the world, the top 10 of which you'll find here.

You find the full ranking, which includes separate lists of top hospitals from 21 countries including the U.S., as well as exceptional specialty hospitals in cardiology, oncology, orthopedics and pediatrics, here.

The largestand originalMayo Clinic has been in Rochester, Minnesota, since 1889. Every year, approximately 1.3 million people from 138 countries come to the Mayo Clinic's 19 hospitals in five states for their specialized team approach. With over 4,800 staff physicians and scientists and over 4,000 full-time research personnel, it is committed to finding answers to the toughest medical cases. Always on the cutting edge, the clinic recently announced several new cancer initiatives. In a counterintuitive move, researchers in Rochester found that by encouraging cancers to mutate, the cancers can be targeted by immunotherapy, and clinical trials for pediatric patients with brain tumors will put this into practice shortly. It also recently announced an agreement to build the first carbon ion therapy treatment center in North America to treat challenging cancers at its Jacksonville, Florida, campus. Patients who seek out the Mayo Clinic appreciate the convenience of its rapid, same-day test results and free concierge services to assist with logistics and travel advice. MayoClinic.org

Cleveland Clinic has always made patient care its centerpiece, and it takes to heart its motto: "Care for the patient as if they are your own family." Historically, Cleveland has also been known for medical breakthroughs and organ transplants, including the first face transplant in the United States. In 2019, it broke its own organ transplant records897, up 3 percent from the year beforeincluding the world's first single-port robotic kidney transplant, which allows for a single small incision and limits the need for postoperative opioids for pain relief. Cleveland's health system encompasses 18 full-service locations systemwide. In 2018, there were 7.9 million outpatient visits, from 185 countries, across all of its campuses. My.ClevelandClinic.org

Over 200 years old and the original and largest teaching hospital of Harvard Medical School, Massachusetts General Hospital is known for its cutting-edge research. Mass General doctors put the insights they gather from that research to good use when diagnosing and treating the nearly 1.6 million patients who walk through its doors annually. With an annual budget of more than $850 million for research and more than 1,200 clinical trials taking place at any time, it is no wonder that Mass General publishes more research articles in prestigious medical journals and receives more federal funding than any other independent hospital in the country. Its researchers' findings range from linking sleep timing and teen obesity to tagging cells using laser particles so as to better understand the growth ofand treattumors. MassGeneral.org

Since 1819, Toronto General Hospital has been a leader in cardiac care, organ transplants and the treatment of complex patient needs. TGH has focused on novel therapies to treat endocrine and autoimmune disorders ever since insulin was developed, and its first clinical use in the treatment of diabetes at the hospital was in 1922. This past year, TGH doctors performed the first robot-assisted brain surgery on a live patient, which they hope will bridge even more frontiers and eventually allow patients in remote communities to get this kind of life-saving care. Its five-year strategic plan focuses on patient well-being and provides regular, transparent performance reviews of health outcomes and patient experience. Uhn.ca

Given that Charit was founded in 1710 when bubonic plague threatened Berlin, it is fitting that, in what is now one of the largest university hospitals in Europe, Charit researchers are taking the lead on identifying and treating infectious diseases such as Zika, SARS and MERS. Charit researchers developed the first diagnostic test to identify the COVID-19 coronavirus, which originated in Wuhan, China. More than half of all German Nobel Prize winners in physiology or medicine can be claimed by Charit as one of its own, and the hospital is internationally renowned for its excellence in teaching and training. In a new partnership announced in July 2019, Charit is integrating the Berlin Institute of Health under its umbrella; according to a statement from the BIH, it "is to becomealongside patient care and the medical facultythe third pillar of Charit." Charite.de

The Johns Hopkins Hospital, founded in 1889 in Baltimore, is not only a leading teaching and research hospital, but it is also central to the history and development of American medical education. William Osler, one of the hospital's founding physicians, invented the idea of medical residency, taking students out of the lecture halls and onto the wards to examine patients. Today Johns Hopkins has 1,162 beds and more than 2,400 full-time attending physicians. Among other firsts, Johns Hopkins was the first hospital in the U.S. to perform male-to-female sex-reassignment surgery. HopkinsMedicine.org

The lineage of this hospital, the first in Zurich, dates back to 1204. It is one of five university hospitals in Switzerland. Currently, it has 43 departments and institutes, ranging from a center on aging and mobility to a department of surgery and transplantation. The hospital has 980 beds, and 1,500 physicians and scientists. It treats over 42,000 inpatients and has over 500,000 outpatient visits every year. In 1977, a physician here successfully restored normal blood flow to constricted coronary arteries using a balloon catheter. Today, the procedure is widely used all over the world. En.Usz.ch

The oldest and largest hospital in this city-state, Singapore General Hospital, a teaching hospital, was founded 1821. Now, it employs more than 10,000 people and sees more than 1 million patients every year. It is home to Southeast Asia's only full multidisciplinary center for cancer and is an acute tertiary referral hospital with over 40 clinical disciplines. In 2010, it was the first hospital in Asia to receive the Magnet designation for nursing excellence from the American Nurses Credentialing Center. Sgh.com.sg

The Sheba Medical Center at Tel Hashomer, near Tel Aviv, serves as Israel's national research and university-affiliated training hospital. It was founded in 1948 as the country's first military hospital. Today, it collaborates with biotech and pharmaceutical companies around the world to develop new drugs and treatments. Serving more than 1.6 million patients a year, its facilities include an acute care hospital, a rehabilitation hospital, a women's hospital, a children's hospital, an eating disorders clinic, a post-traumatic stress disorder clinic forsoldiers and an outpatient clinic. Its research specialties include cardiology, cancer, brain diseases, obstetrics and gynecology, genetics and medical education. https://eng.sheba.co.il/

This hospital, with about 15,000 employees and 1,340 beds, is affiliated with the Karolinska Institute, which was founded in 1810 by King Karl XIII as a school for military surgeons, given the alarm about death rates in army field hospitals. Today it is one of the largest and most prestigious medical schools in the world. The facility incorporates two children's hospitals and is known for its specialties in reproductive medicine, fetal medicine, surgery, urology and neurosurgery. It is a member of 18 referral networks across Europe concentrating on rare diseases. Karolinska.se

Visit http://www.newsweek.com/best-hospitals-2020 for the remaining Top Best Hospitals in the World.

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The Top 10 Hospitals In the World - Newsweek