VANCOUVER, British Columbia--(BUSINESS WIRE)--Novelogics Biotechnology, Inc. announced today that it has entered into a research agreement with The Centre for Drug Research and Development (CDRD), Canadas national drug development and commercialization centre, to further characterize Novelogics' internally-developed antibody immunotherapy for treating cancer.
The proprietary technology behind Novelogics innovation involves discovery and development of monoclonal antibodies that target a protein that promotes immune suppression in cancer patients. It is predicted that this new therapy could treat a broad range of cancers, and because it works with the patients own immune system, it would be safer and less toxic with fewer debilitating side-effects.
CDRD will be analyzing the technology through custom in vitro assays that will help validate and identify their lead antibody and move it towards a Phase 1 clinical trial as early as 2019. The technology has recently shown preliminary evidence of tumour inhibition in a prostate cancer model and based on results from CDRDs research, it could be expanded to other cancer models.
Novelogics President and Chief Scientific Officer Dr. Wayne Cheney stated, We are excited to introduce our novel approach to treating cancer. Unlike other immunotherapies that function by modulating, inhibiting or blocking targets, our innovative drug works by intercepting. This is a new way of limiting the immune suppressive effects of the drug target, which offers a huge opportunity to make a difference in the fight against cancer. We look forward to a successful collaboration with CDRD and are thrilled to be working with their technical team of experts and state-of-the-art biologics facility.
CDRDs Head of Biologics Dr. Ismael Samudio commented, This work with Novelogics is an exciting opportunity for CDRD to apply our scientific expertise in NK cell biology and therapeutic antibodies to a technology that has very promising pre-clinical potential. This a great example of how CDRD is partnering with Canadian life sciences companies to advance promising discoveries and transform them into validated investments and improved health outcomes. By combining our expertise and specialized infrastructure, we aim to provide critical data to advance Novelogics technology and help bring new therapeutic treatments to market.
It is anticipated that a pre-clinical candidate antibody will be selected in 2017, and that further clinical development activities will follow.
About Novelogics Biotechnology, Inc.
Novelogics Biotechnology Inc. is virtual life sciences company utilizing expertise at a variety of Contract Research labs and is dedicated to developing innovative cancer treatments that harness the power of the immune system to help eradicate tumors more naturally. Their immunotherapy concepts focus on development of antibody therapeutics and have the potential to treat multiple cancer types without the side-effects associated with traditional cancer therapies. We anticipate the technology will be well-received by larger biotechnology and pharmaceutical companies seeking novel antibody immunotherapy treatments in this exciting area of cancer drug development. Novelogics has one mission in mind we want to create better cancer treatments. http://www.novelogics.com
Novelogics Biotechnology Inc. is a privately-owned corporation operating in Vancouver, Canada.
About The Centre for Drug Research and Development (CDRD)
CDRD is Canadas national drug development and commercialization centre working in partnership with academia, industry, government and foundations. CDRD provides the specialized expertise and infrastructure to identify, validate and advance promising discoveries, and transform them into commercially viable investment opportunities for the private sector and ultimately into new therapies for patients. Canadas Networks of Centres of Excellence Program has recognized CDRD as a Centre of Excellence for Commercialization and Research (CECR). http://www.cdrd.ca
Originally posted here:
Novelogics Biotechnology, Inc. & CDRD Partner to Advance Novel Cancer Treatment - Business Wire (press release)
- Production of ethanol from winter barley by the EDGE (enhanced dry grind enzymatic) process [Last Updated On: August 17th, 2024] [Originally Added On: April 29th, 2010]
- A high-throughput transient gene expression system for switchgrass (Panicum virgatum L.) seedlings [Last Updated On: August 17th, 2024] [Originally Added On: May 8th, 2010]
- Cellulose crystallinity index: measurement techniques and their impact on interpreting cellulase performance [Last Updated On: August 17th, 2024] [Originally Added On: May 25th, 2010]
- Comparing the fermentation performance of Escherichia coli KO11, Saccharomyces cerevisiae 424A(LNH-ST) and Zymomonas mobilis AX101 for cellulosic ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: May 28th, 2010]
- Enzymatic digestibility and ethanol fermentability of AFEX-treated starch-rich lignocellulosics such as corn silage and whole corn plant [Last Updated On: August 17th, 2024] [Originally Added On: June 10th, 2010]
- Improved xylose and arabinose utilization by an industrial recombinant Saccharomyces cerevisiae strain using evolutionary engineering [Last Updated On: August 17th, 2024] [Originally Added On: June 16th, 2010]
- Effects of enzyme feeding strategy on ethanol yield in fed-batch simultaneous saccharification and fermentation of spruce at high dry matter [Last Updated On: August 17th, 2024] [Originally Added On: June 26th, 2010]
- Impact of dual temperature profile in dilute acid hydrolysis of spruce for ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: July 2nd, 2010]
- Ethanol production from mixtures of wheat straw and wheat meal [Last Updated On: August 17th, 2024] [Originally Added On: July 6th, 2010]
- Earning Cash – Selling Old Mobile Phones [Last Updated On: August 17th, 2024] [Originally Added On: July 7th, 2010]
- Earning Cash – Selling Old Mobile Phones [Last Updated On: August 17th, 2024] [Originally Added On: July 7th, 2010]
- Improving simultaneous saccharification and co-fermentation of pretreated wheat straw using both enzyme and substrate feeding [Last Updated On: August 17th, 2024] [Originally Added On: August 3rd, 2010]
- Practical screening of purified cellobiohydrolases and endoglucanases with alpha-cellulose and specification of hydrodynamics [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Techno-economic evaluation of stillage treatment with anaerobic digestion in a softwood-to-ethanol process [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Cross-reactions between engineered xylose and galactose pathways in recombinant Saccharomyces cerevisiae [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Rapid optimization of enzyme mixtures for deconstruction of diverse pretreatment/biomass feedstock combinations [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2010]
- Automated saccharification assay for determination of digestibility in plant materials [Last Updated On: August 17th, 2024] [Originally Added On: November 7th, 2010]
- Biodetoxification of toxins generated from lignocellulose pretreatment using a newly isolated fungus, Amorphotheca resinae ZN1, and the consequent ethanol fermentation [Last Updated On: August 17th, 2024] [Originally Added On: November 28th, 2010]
- Lignin monomer composition affects Arabidopsis cell-wall degradability after liquid hot water pretreatment [Last Updated On: August 17th, 2024] [Originally Added On: December 11th, 2010]
- Thermostable endoglucanases in the liquefaction of hydrothermally pretreated wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: February 6th, 2011]
- Cellulose accessibility limits the effectiveness of minimum cellulase loading on the efficient hydrolysis of pretreated lignocellulosic substrates [Last Updated On: August 17th, 2024] [Originally Added On: February 14th, 2011]
- Arsenal of plant cell wall degrading enzymes reflects host preference among plant pathogenic fungi [Last Updated On: August 17th, 2024] [Originally Added On: February 16th, 2011]
- Hemicellulases and auxiliary enzymes for improved conversion of lignocellulosic biomass to monosaccharides [Last Updated On: August 17th, 2024] [Originally Added On: February 22nd, 2011]
- Two-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase [Last Updated On: August 17th, 2024] [Originally Added On: March 6th, 2011]
- Topochemical distribution of lignin and hydroxycinnamic acids in sugar-cane cell walls and its correlation with the enzymatic hydrolysis of polysaccharides [Last Updated On: August 17th, 2024] [Originally Added On: March 17th, 2011]
- Direct ethanol production from cellulosic materials using a diploid strain of Saccharomyces cerevisiae with optimized cellulase expression [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2011]
- Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenome library [Last Updated On: August 17th, 2024] [Originally Added On: May 8th, 2011]
- Low temperature lignocellulose pretreatment: effects and interactions of pretreatment pH are critical for maximizing enzymatic monosaccharide yields from wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: May 15th, 2011]
- Effect of mixing on enzymatic hydrolysis of steam-pretreated spruce: a quantitative analysis of conversion and power consumption [Last Updated On: August 17th, 2024] [Originally Added On: May 15th, 2011]
- Thermostable recombinant xylanases from Nonomuraea flexuosa and Thermoascus aurantiacus show distinct properties in the hydrolysis of xylans and pretreated wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: May 22nd, 2011]
- Investigation of tension wood formation and 2,6-dichlorbenzonitrile application in short rotation coppice willow composition and enzymatic saccharification [Last Updated On: August 17th, 2024] [Originally Added On: May 29th, 2011]
- Aiming the complete utilization of sugar beet pulp through mild acid and hydrothermal pretreatment followed by enzymatic digestion [Last Updated On: August 17th, 2024] [Originally Added On: June 5th, 2011]
- Alkaline peroxide pretreatment of corn stover: effects of biomass, peroxide, and enzyme loading and composition on yields of glucose and xylose [Last Updated On: August 17th, 2024] [Originally Added On: June 12th, 2011]
- In-situ lignocellulosic unlocking mechanism in termite for carbohydrate hydrolysis: critical lignin modification [Last Updated On: August 17th, 2024] [Originally Added On: June 19th, 2011]
- Supplementation with xylanase and beta-xylosidase to reduce xylo-oligomer and xylan inhibition of enzymatic hydrolysis of cellulose and pretreated corn stover [Last Updated On: August 17th, 2024] [Originally Added On: June 26th, 2011]
- Co-hydrolysis of hydrothermal and dilute acid pretreated Populus slurries to support development of a high-throughput pretreatment system [Last Updated On: August 17th, 2024] [Originally Added On: July 17th, 2011]
- Evaluation of preservation methods for improving biogas production and enzymatic conversion yields of annual crops [Last Updated On: August 17th, 2024] [Originally Added On: July 24th, 2011]
- Simultaneous saccharification and co-fermentation of lignocellulosic residues from commercial furfural production and corn kernels using different nutrient media [Last Updated On: August 17th, 2024] [Originally Added On: July 31st, 2011]
- Increased isobutanol production in Saccharomyces cerevisiae by overexpression of genes in valine metabolism [Last Updated On: August 17th, 2024] [Originally Added On: July 31st, 2011]
- Bioprospecting metagenomics of decaying wood: mining for new glycoside hydrolases [Last Updated On: August 17th, 2024] [Originally Added On: August 7th, 2011]
- Functional characterization of cellulases identified from the cow rumen fungus neocallimastix patriciarum W5 by transcriptomic and secretomic analyses [Last Updated On: August 17th, 2024] [Originally Added On: August 21st, 2011]
- Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum [Last Updated On: August 17th, 2024] [Originally Added On: August 28th, 2011]
- Conversion of deoxynivalenol to 3-acetyldeoxynivalenol in barley derived fuel ethanol co-products with yeast expressing trichothecene 3-O-acetyltransferases [Last Updated On: August 17th, 2024] [Originally Added On: September 4th, 2011]
- Comparative performance of precommercial cellulases hydrolyzing pretreated corn stover [Last Updated On: August 17th, 2024] [Originally Added On: September 11th, 2011]
- Impact of pretreatment and downstream processing technologies on economics and energy use in cellulosic ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: September 11th, 2011]
- A kinetic model for quantitative evaluation of the effect of H2 and osmolarity on hydrogen production by Caldicellulosiruptor saccharolyticus [Last Updated On: August 17th, 2024] [Originally Added On: September 18th, 2011]
- High level secretion of cellobiohydrolases by Saccharomyces cerevisiae [Last Updated On: August 17th, 2024] [Originally Added On: September 18th, 2011]
- How recombinant swollenin from Kluyveromyces lactis affects cellulosic substrates and accelerates their hydrolysis [Last Updated On: August 17th, 2024] [Originally Added On: September 25th, 2011]
- Bio-conversion of paper sludge to biofuel by simultaneous saccharification and fermentation using a cellulase of paper sludge origin and thermotolerant Saccharomyces cerevisiae TJ14 [Last Updated On: August 17th, 2024] [Originally Added On: October 2nd, 2011]
- Biogenic hydrogen and methane production from Chlorella vulgaris and Dunaliella tertiolecta biomass [Last Updated On: August 17th, 2024] [Originally Added On: October 2nd, 2011]
- The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistic effect? [Last Updated On: August 17th, 2024] [Originally Added On: October 9th, 2011]
- Biotechnology [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- Biology: Biotechnology: Gene Cloning [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- What Does a Biotechnology Course Look Like? [Last Updated On: August 17th, 2024] [Originally Added On: October 10th, 2011]
- Demo day by SCT Biotechnology Branch 2011 passouts [Last Updated On: August 17th, 2024] [Originally Added On: October 12th, 2011]
- Biotechnology Program Video [Last Updated On: August 17th, 2024] [Originally Added On: October 12th, 2011]
- Introduction To Industrial Biotechnology [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2011]
- MSc Molecular Biotechnology -- Come to the School of Biosciences, University of Birmingham, UK - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2011]
- Oxbridge Biotechnology Roundtable - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- fermentation technology (biotechnology practical class) UNIVERSITY OF MALAYA - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- Biotechnology: Learn about New Biological Medicines in Development - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 15th, 2011]
- Improving L-arabinose utilization of pentose fermenting Saccharomyces cerevisiae cells by heterologous expression of L-arabinose transporting sugar transporters [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- The promoting effect of by-products from Irpex lacteus on subsequent enzymatic hydrolysis of bio-pretreated cornstalks [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- BiotechNaukri #Biotechnology Jobs - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- bio-technology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 16th, 2011]
- BioBytes - Biotechnology and food flavoring - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 19th, 2011]
- Stine Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 22nd, 2011]
- Effects of alkaline or liquid-ammonia treatment on crystalline cellulose: Changes in crystalline structure and effects on enzymatic digestibility [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Transcriptome analysis of Aspergillus niger grown on sugarcane bagasse [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- A cellular automaton model of crystalline cellulose hydrolysis by cellulases [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Application of a Burkholderia cepacia lipase-immobilized silica monolith to the batch and continuous biodiesel production with a stoichiometric mixture of methanol and crude Jatropha oil [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- Algal Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 24th, 2011]
- Techniques of Biotechnology, Part 1 of 4 - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 25th, 2011]
- Biotechnology days in Macedonia II - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- BioBytes: Forensics and Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Faces of Biotechnology: What is Biotechnology - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Mucosal and systemic responses/Dr Thomas Muster-AVIR Green Hills Biotechnology-World Vaccine - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 26th, 2011]
- Unlimited Income Potential in Bio-Technology, Part 1 - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 27th, 2011]
- Islam Ahmadiyya Questions: Biotechnology, Portraits, Ring, Prayers, Dreams, Adopted Children - Video [Last Updated On: August 17th, 2024] [Originally Added On: October 28th, 2011]