Xanax, Valium may increase dementia risk in older adults

By MyHealthNewsDaily staff

Older adults taking psychiatric medications such as Valium or Xanax may be at increased risk of dementia, a new French study suggests.

In the reports, adults older than 65 who took drugs known as benzodiazepines were 50 percent more likely to develop dementia over a 15-year period, compared with those who did not take the drugs.

Benzodiazepines are widely prescribed medications, used to treat symptoms of anxiety and sleep disorders.

The study findings held true even when taking into account other factors that may affect people's dementia risk, such as age, gender, diabetes and early signs of dementia. The researchers also accounted for some factors that lead people to start taking benzodiazepines in the first place.

Researchers caution that the study only found an association between the drugs and dementia, and not a direct cause-and-effect link.

However, the findings agree with those of several earlier studies looking at the link between benzodiazepines and dementia. Use of the medications has also been tied to other serious events in older adults, such as falls.

"Considering the extent to which benzodiazepines are prescribed and the number of potential adverse effects of this drug class in the general population, [their] indiscriminate, widespread use should be cautioned against," the researchers said.

Whenever possible, use of the drugs should be limited to just a few weeks, the researchers said. Currently, despite evidence that the drugs work only over short periods, many people take them for years.

The study followed about 1,000 older adults living in France who, at the study's start, did not have dementia and were not taking benzodiazepines. Over the first five years of the analysis, 95 participants started taking benzodiazepines.

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Xanax, Valium may increase dementia risk in older adults

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