Urinary continence (UC) represents the main non-oncological goal in patients undergoing robotic-assisted radical prostatectomy (RARP). To evaluate the efficacy in early UC achievement, we described a new sling technique using the retrotrigonal muscular layer (TZ sling) combined with total anatomical reconstruction (TAR).

We prospectively enrolled 407 consecutive prostate cancer (PC) patients undergoing RARP between May 2017 and January 2020. The first 250 patients underwent only TAR, while the following 157 patients TAR+TZ sling, by isolating and anchoring the retrotrigonal muscular layer to the pubic bone with 2 bilateral sutures. We defined UC as1 pad/die, which was assessed after catheter removal at 1, 4 and 12wk using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) score. Sling-related operative time and post-operative complications were analyzed.

In the TAR group, the UC rates at the 1, 4 and 12wk were 58%, 66% and 86%; in the TAR+TZ sling group 72%, 76% and 88%, respectively. A statistically significant difference was observed in the two groups at 1wk (p=0.0049) and 4wk (p=0.035) favoring the TZ sling surgical strategy. This difference in UC rates was lost at 12wk (p0.05). No statistically significant differences in operative time, acute urinary retentions and other complication rates were observed between the two groups (p=NS).

We have described a new, safe, feasible modification of RARP using a sling with the retrotrigonal muscular layer associated with TAR. We have demonstrated a statistically significant improvement in early UC rate in patients who are undergoing TAR and TZ sling compared to undergoing only TAR.

World journal of urology. 2020 Oct 28 [Epub ahead of print]

Matteo Luigi Zanoni, Fabio Grizzi, Davide Maffei, Paolo Vota, Nicola Frego, Giovanni Toia, Cinzia Mazzieri, Massimo Lazzeri, Nicol Buffi, Giovanni Lughezzani, Paolo Casale, Alberto Saita, Giorgio Guazzoni, Alberto Mandressi, Gianluigi Taverna

Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy., Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy., Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089, Rozzano, Italy., Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy. .

PubMed http://www.ncbi.nlm.nih.gov/pubmed/33112984

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Retrotrigonal muscular layer sling associated with total anatomical reconstruction in robot-assisted radical prostatectomy and early continence. -...