Grey's Anatomy has seen many of its most popular characters say goodbye to the Grey Sloan Memorial Hospital over the past few years. The first major farewell was that of Dr Cristina Yang (played by Sandra Oh) who left in 2014. Despite moving onto new projects, Oh is still asked the same question time and time again.

WARNING: This article contains spoilers from Grey's Anatomy.

Cristina was Dr Meredith Grey's (Ellen Pompeo) no nonsense best friend who fans greatly admired for her confidence and wit.

She knew her own mind and wasn't afraid to speak it, even when it wasn't always in her favour to do so.

Cristina supported Meredith throughout a lot of the drama until her former fianc suddenly showed up in season 10.

Little did fans know that this was the beginning of the end for Cristina on Grey's Anatomy.

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Preston Burke (Isaiah Washington) called off the wedding after he realised she didn't really want to go through with marrying him.

To save her from ending it, Preston stopped the big day himself and left the series.

When he did briefly return in 2014, Preston offered Cristina an opportunity she couldn't refuse.

Preston was moving to Italy with his wife and so said he needed someone to take over his medical facility in Zurich, Switzerland.

With a heavy heart at leaving Meredith behind, Cristina packed up her bags and left for good.

Speaking to The Hollywood Reporter at the time about the decision to make her exit, actress Oh explained: "Creatively, I really feel like I gave it my all, and I feel ready to let her go.

Its such an interesting thing to play a character for so long and to actually get the sense that she wants to be let go as well.

[Cristina] wants to be let go, and I am ready to let her go.

In a recent interview with ET Canada, Oh was once again asked the all important question: Would she return to Grey's Anatomy for its final ever episode?

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Oh said: "I wish I had a dollar for the number of times [I've been asked this question].

"It's OK, I'm happy to answer it, I'm extremely grateful you're asking me that question because that means people are still invested in Cristina Yang, a character who I left six years ago.

"[But] there are so many new projects and I'm a different person so I'm going to have to say no."

While fans will be disappointed to hear this, it doesn't seem like Grey's Anatomy is going to be ending any time soon.

In July, cast members Kim Raver, Camilla Luddington and Kevin McKidd all signed three-year contracts for Grey's Anatomy.

This means ABC are already looking to the future of the medical drama.

Creator Shonda Rhimes has previously said though Grey's Anatomy will continue just so long as actress Pompeo wants to still be in it.

As of writing this article, Pompeo hasn't signed up for another series beyond season 17 so the future of Grey's Anatomy really does lie with her.

Grey's Anatomy is available to watch on ABC.

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Grey's Anatomy: Will Sandra Oh return as Cristina Yang for last ever episode? - Daily Express