Khalid Ali,1 Salma MS El Said,2 Nermien N Adly,2 Samia A Abdul-Rahman2

1Academic Department of Geriatrics, Brighton and Sussex Medical School, Brighton, UK; 2Geriatrics and Gerontology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Correspondence: Salma MS El SaidGeriatrics and Gerontology Department, Faculty of Medicine, Ain Shams University, Emtedad Ramsis Street, Abbasia, Cairo, EgyptTel +201222202878Email Salma_elsaid@med.asu.edu.eg

Background: Obesity and osteoporosis are two conditions that are associated with morbidity and mortality; there is contradictory evidence regarding this association.Purpose: The aim of the current study was to explore further the association between obesity and calcaneus stiffness index (CSI), as a measure of bone density, in a community-based cross-sectional study in an Egyptian population.Methods: A cross-sectional study was conducted among active subjects, aged 20 years old, over one year. CSI was measured by Quantitative ultrasound (QUS), in addition; QUS T-score and Z-score of the non-dominant heel scan were recorded.Results: Two hundred and eighty participants were recruited; 7 subjects were excluded because of Z score more than 2, mean age was 61 ( 11.9) years, and mean BMI was 29.7 (5.6). Female participants were 77.7%, with mean of age 60.3 ( 11.6); and age range 2082 years. Male participants were 22.3%, with mean of age 63.6 ( 12.7); and age range 3080 years. Older subjects (>55 years) had significantly lower CSI and worse T-score than the younger subjects (P < 0.001 for both). In the younger age group, BMI was not significantly associated with CSI, even after adjustment for gender (P= 0.52). However, in the older age group, BMI was significantly associated with stiffness index (P= 0.049, O.R.= 1.73), even after adjustment for gender (P= 0.041, O.R.= 1.7).Conclusion: Compared to young subjects, older subjects (55 years) had significantly lower bone strength as measured by CSI, and their BMI was significantly positively associated with bone density. In younger people(<55 years), BMI was not associated with bone strength.

Keywords: BMI, bone, obesity, QUS, stiffness index

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The Relation Between Calcaneus Stiffness Index as a Measure of Bone De | JMDH - Dove Medical Press