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Joseph Izatt 2009
March 16, 2009 OSEP-COSI Seminar by Professor Joseph A. Izatt, Department of Biomedical Engineering, Duke University, Durham, North Carolina "Optical Coherence-Based Imaging And Sensing In Biomedicine And Biotechnology" Optical coherence-based imaging techniques including optical coherence tomography (OCT), optical coherence microscopy (OCM), and spectral domain phase microscopy (SDPM) use low-coherence spectral interferometry to obtain nanometer to micron-scale measurements of structure, motion, and molecular composition in living cells, tissues, and organisms. OCT has become a standard diagnostic tool in clinical ophthalmology, and is under investigation for other human diagnostic applications including cancer detection and evaluation of cardiovascular disease. Within the past few years, dramatic technology advances have increased the performance of OCT and OCM systems manyfold, and are now capable of micron-scale two and three-dimensional functional and molecular imaging noninvasively in living systems. Applications of these new technologies for noninvasive, quantitative characterization of ophthalmic disease progression, and for high-throughput phenotyping of small animal models of disease and genetic manipulation are particularly compelling. Related technology advances have enabled the design of highly phase-stable interference microscopes capable of resolving nanometer-scale structures and motions in living cells with ms temporal resolution. These new capabilities ...From:COSICUBViews:0 0ratingsTime:01:00:05More inScience Technology

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Joseph Izatt 2009 - Video