June 21, 2012 - According to "Biotechnology: Bringing Innovation to Neglected Disease Research and Development," small- to medium-sized biotech companies bring innovation to global health. Findings show that 134 biotechnology companies are participating in neglected disease research and development, which represents participation in 39% of 191 new drugs, vaccines, and diagnostics in development. Report also finds that 64% of all products in development by biotech companies involve partnering. Biotechnology Industry Organization 1201 Maryland Ave., SW, Ste. 900 Washington, DC, 20024 USA Press release date: June 18, 2012

The new report will be released today at the 2012 BIO International Convention in Boston, Mass.

2012 BIO International Convention 2012 BIO International Convention:Biotechnology Industry Organization WASHINGTON--Small- to medium-sized biotechnology companies are bringing innovation to global health, according to a report published today by BIO Ventures for Global Health (BVGH) and the Biotechnology Industry Organization (BIO). The report shows that 134 biotechnology companies are participating in neglected disease research and development, which represents participation in 39% of the 191 new drugs, vaccines, and diagnostics in development for neglected diseases such as malaria, tuberculosis, dengue fever, and others.

"It is encouraging that small- to medium-sized biotechnology companies that lead the charge in developing life-saving medicines and technologies in the developed world are so engaged in creating new drugs, vaccines, and diagnostics for the neglected diseases primarily affecting the poor in the developing world"

Partnering is an important driver for today's biotechnology companies. The new report, Biotechnology: Bringing Innovation to Neglected Disease Research and Development, finds that 64% of all products in development by biotechnology companies across the pipeline of drugs, vaccines, and diagnostics for neglected diseases involve partnering.

According to the report, product development partnerships (PDPs) - a unique public-private partnering mechanism created to increase biopharmaceutical participation in neglected disease R&D, government agencies, and academic institutions - are driving this biotechnology company partnering for neglected diseases. Although PDPs are the focal point of industry engagement in global health, they are the second most frequent partner to biotechnology companies after academia with involvement in 52% of partnered projects. When a PDP is not involved in a project, biotechnology partnerships with government agencies increase, especially for vaccines and diagnostics.

Across all neglected diseases, biotechnology companies work alone 36% of the time, according to the report. For tuberculosis and dengue fever, companies more frequently overcome barriers and leverage some market potential to work alone. This may be because small to medium-sized companies perceive a potential market opportunity.

"We were very pleased to see the level of the biotechnology sector's engagement in global health research and development, as a critical source of innovation. To continue progress in addressing the unmet medical needs of the developing world, both biotechnology companies and global health groups should ramp up commitment and involvement," says Don Joseph, CEO of BVGH. "Our new report provides specific recommendations both to biotechnology companies and neglected disease stakeholders from academia, governments, nonprofits, and foundations to increase and improve their collaborative work in neglected disease research. Accelerating solutions for these devastating diseases presents major challenges but can happen if these groups continue and increase their work together."

While the report finds that small to medium-sized biotechnology companies are involved in 39% of all projects for neglected disease, BIO estimates there are nearly 3,000 public and private biotechnology companies worldwide. At least 90% of these companies focus on health research and development, suggesting that the 134 biotechnology companies participating in neglected disease research and development identified in the report represent about 5% of global biotechnology companies.

"It is encouraging that small- to medium-sized biotechnology companies that lead the charge in developing life-saving medicines and technologies in the developed world are so engaged in creating new drugs, vaccines, and diagnostics for the neglected diseases primarily affecting the poor in the developing world," says Jim Greenwood, President and CEO of BIO. "The true value of this week's BIO International Convention is to bring together industry leaders who can share insights and engage in discussions focused on potential collaborations that could lead to scientific breakthroughs that will address these and other global challenges."

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