LAS VEGAS (KTNV) Four people died Monday night in a wrong-way crash on Interstate 15 south of Las Vegas, according to the Nevada State Police Highway Patrol.

The collision happened when a Cadillac headed northbound in the southbound lanes crashed head-on into a Toyota pickup truck. The truck caught fire, killing all three people inside, officials said.

The driver of the Cadillac, an adult female, was also killed. Officials said they believe she may have been driving under the influence of alcohol.

Three vehicles swerved to avoid the head-on crash, including a semi-truck. Two people from those vehicles were hospitalized, officials said.

Southbound traffic was shut down at Sloan, approximately 18 miles southwest of Las Vegas, where drivers were being diverted off the interstate. Drivers were directed to access Las Vegas Boulevard to head southbound from there.

As of 10 p.m. Monday, drivers should expect southbound lanes to remain shut down in the area for approximately 5 hours, NSP said.

Nevada State Police officials noted this crash marks the first wrong-way fatalites in Southern Nevada this year.

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4 people killed in wrong-way crash that shut down traffic on I-15 south of Las Vegas - KTNV Las Vegas