Quantum dot biosensors for ultrasensitive multiplexed diagnostics

In many diagnostic processes, the detection of several protein markers is required. Rather than performing several sequential analysis steps, a multiplexed approach allows the simultaneous measurement of multiple biomarkers from the same blood sample. The convergence of nanotechnology, microtechnology, microfluidics, photonics, signal processing, and proteomics allows for the development of increasingly sophisticated and effective multiplexed point-of-care diagnostic devices. The detection of protein biomarkers can done with an optical multiplexing approach that uses dye particles of different colors. In contrast to conventional fluorescence dyes, quantum dots generate a much more powerful fluorescent signal which provides a large increase in sensitivity compared to other methods. Quantum dots are also available in multiple colors, allowing the investigators to tag each antibody with a uniquely colored quantum dot. Researchers have now demonstrated a novel and fast quantum dot-based FRET technique that is suitable for multiplexed ultrasensitive detection.

Fluorescent probes light up cancerous tumors

Building on his Nobel Prize-winning work creating fluorescent proteins that light up the inner workings of cells, a team of researchers led by Howard Hughes Medical Institute investigator Roger Tsien, PhD, professor of pharmacology, chemistry and biochemistry at the University of California, San Diego and the Moores UCSD Cancer Center has developed biological probes that can stick to and light up tumors in mice.

Nanopartikel und biologische Barrieren

Nanotechnologie und speziell Nanopartikel eroeffnen neue, ungeahnte Moeglichkeiten fuer die Pharmazie und die Medizin. Das Potenzial dieser winzigen Partikel steht im Mittelpunkt einer Konferenz, zu der namhafte Experten und Nachwuchswissenschaftler aus der ganzen Welt an der Universitaet des Saarlandes zusammenkommen.

Tanner EDA and Sound Design Technologies Announce Process Design Kit Collaboration for Thin Film Technologies

Tanner EDA, the catalyst for innovation for the design, layout and verification of analog and mixed-signal integrated circuits (ICs) and Sound Design Technologies (SDT), a leading designer and manufacturer of integrated passives and stacked-die assemblies, are collaborating to develop process design kits for analog/mixed-signal (A/MS) designers using Tanner EDA's HiPer Silicon software.

Celator Pharmaceuticals Selected to Participate in NCI’s Nanotechnology Characterization Laboratory Assay Cascade for Characterization of Nanoparticle Prodrug Delivery Platform

Celator Pharmaceuticals today announced that the National Cancer Institute's (NCI) Nanotechnology Characterization Laboratory (NCL), operated by SAIC-Frederick (Frederick, Maryland), has agreed to conduct characterization studies to advance the development of the company's nanoparticle drug formulation technology.